part 5 Flashcards
What is choleithiasis?
- most common disorder of biliary system
- stones in gallbladder
- stones can migrate to cystic or common bile duct (pain and/or obstruction)
What is cholecystitis?
- inflammation of gallbladder
- usually associated with choleithiasis
- caused from stones or sludge
What are the risk factors for gallbladder disease?
female having kids older than 40 estrogen therapy sedentary lifestyle genetics obesity
this develops when balance that keeps cholesterol, bile salts, and calcium in solution is altered leading to precipitation.
- cause is unknown
- satsis of bile and changes in composition causing biliary sludge
cholelithiasis
What can decrease bile flow?
immobility
pregnancy
inflammatory/obstructive lesions of biliary system
What are the causes of acalculous cholecystitis (inflammation without gallstones)?
- older adults and critically ill
- prolonged immobility, fasting, prolonged parenteral nutrition, diabetes
- bacteria/chemical irritants
- adhesions, neoplasma, anesthesia, opioids
- confined to mucous lining or entire wall
- distended with bile or pus
- cystic duct can become occluded
- scarring and fibrosis after attack
cholecystitis
When will gallbladder disease commonly happen?
3-6 hours after a high-fat meal or when pt lies down
- pt may also be tacky, diaphoretic, prostration (weakness)
- referred pain in shoulder/scapula
What are the clinical manifestations of gallbladder disease when total obstruction occurs?
-dark amber urine
-clay colored stools
pruritus
intolerance to fatty foods
bleeding tendencies
steatorrhea (fat in stool)
-pain
-indigestion
fever/chills
jaundice
pain/tenderness RUQ (referred to right shoulder/scapula)
N/V
restless
diaphoresis
leukocytosis (inflammation)
RUQ or epigastric tenderness
abd rigidity
clinical manifestation of gallbladder disease
- fat intolerance
- dyspepsia (upper abd pain)
- heartburn
- flatulence
chronic cholecystitis
How do we visualize the gallbladder ?
- ultrasound
- ERCP (endoscopic retrograde cholangiopancreatography) goes to bile duct
- percutaneous transhepatic cholangiography