Part 2 acid base Flashcards
Metabolic acidosis=pH is less than 7.35…when you see metabolic=kidneys which equals bicarbonate
bicarbonate level is decreased
bicarbonate is less than 22 in metabolic acidosis
Clinical presentation of metabolic acidosis
Hyperkalemia
pH less 7.2 is what?
severe acidosis
less than 7.2 which is severe acidemia you need urgent treatment
In acidosis potassium level is going up
Alkalosis potassium level is what?
low
Why is patient is having metabolic acidosis you must calculate what?
Anion gap
The anion gap in the human body the amount of cations and anions should be balanced what are the major cations in the blood?
Na+
What are the anions in the body?
chloride and bicarbonate
Unmeasured anions are phosphate, citrate, sulfate,protein, formic acid and these are acidic substances and we don’t measure them so that leaves the gap
When we do electrolyte workup we only measure sodium,potassium,bicarbonate, and chloride
Anion gap=
Na+ - (Cl-+HCO3-)
Why is it important to calculate anion gap? Because if the anion gap is high you have more of unmeasured anions in your body
If pt is in metabolic acidosis next job is to calculate anion gap
If anion gap is high these are the causes that can contribute to metabolic acidosis such as methanol, uremia, etc
If someone ingest large amounts of methanol pt may go into elevated anion gap metabolic acidosis why is that what is the end product? Alcohol goes into what? aldehyde goes into what acid
formic acid
Alcohol metabolizes to aldehyde…aldehyde is to acid
Once you ingest methanol it will convert to formic acid in the end
Lactic acidosis causes metabolic acidosis