Anemia powerpoint Flashcards
When patient has anemia what does a person feel like?lightheaded,__________,________
tired, worn out
Anemia is defined by the World Health Organization (WHO)
as a hemoglobin (Hb) concentration
<_______g/dL for adult males and postmenopausal women
<13.0 g/dL
Anemia is defined by the World Health Organization (WHO)
as a hemoglobin (Hb) concentration
<______g/dL for premenopausal women
<12.0 g/dL
Even with treatment, many patients with Anemia in CKD will fall into the “anemic” range
With anemia prevalence increases as eGFR __________ (as pt’s kidney function declines they are at risk for worse outcomes)
declines
If prevalence is going to increase as your GFR declines what do you think that means as far as things like screening? More frequent screening is needed as pt’s GFR declines
Clinical Presentation of Anemia
Patients may be asymptomatic
Fatigue, SOB (shortness of breath), chest pain, tachycardia, tingling in the extremities, general malaise, headaches, cold intolerance
All patients are screened for anemia when they are first evaluated for CKD with a ________________ (CBC)
complete blood count
If found to have low hemoglobin, should have further evaluation
CBC, Red blood cell (RBC), reticulocyte count, serum iron, total iron-binding
capacity (TIBC), percent transferrin saturation (TSAT), serum ferritin, serum folate
vitamin B12 levels, test for occult blood in stool (Tsat) = (serum iron/TIBC) x 100%
Why do we do so many labs? to see if something is causing anemia maybe pt has a GI bleed and thats why they have low hemoglobin levels
Why are we looking at vitamin B12 or folate?
someone might have a deficiency and we need to replete these things before giving them therapies
If no underlying cause found, continue to screen all patients with CKD
Frequency of testing for anemia
For CKD pts w/o anemia measure Hb concentration when clinically indicated and at least __________in pts with CKD3
at least _____per year in pts with CKD 4-5ND (ND is not on dialysis)
at least 3 every 3 months in pts w/CKD 5HD and CKD 5PD (HD is hemodialysis and PD is peritoneal dialysis)
annually
twice per year
Pts with CKD 3 (so 3a and 3b) is GFR at what range?
30-59
Screening for anemia we look at ________deficiency
iron deficiency
___________:primary cause of resistance to treatment of anemia with standard therapy. If pts don’t have adequate iron stores they could be potentially resistant to ESAs
iron deficiency
ESAs (erthropoeitn stimulating agents) are retacrit and procrit
Why do we screen for HIV and malignancies? pts with these disease states have ____immune systems
weakened
Diagnosis of anemia
Diagnose anemia in adults and children >15 years with CKD when the Hb concentration is less than 13.0g/dl in males and less than 12 in females