Parkinsons Flashcards
What medication is used to treat parkinsons disease?
Dopamine cant cross the BBB so L-Dopa was created.
Co-careldopa is a mixture of carbidopa and levodopa;
What is MAO-B inhibitors and how do they work ???
MAO–B inhibitors can help your nerve cells make better use of the dopamine that they have. Monoamine oxidase type B is an enzyme that wrongly hoovers up dopamine that is not being used by your brain. MAO-B inhibitors stop this enzyme so that more dopamine becomes available to treat your symptoms
What are the two selective MAO-B inhibitors ?
Selegilline
Rasagiline
How do dopamine receptor agonist work ?
Dopamine agonist drugs trick your brain into thinking they are dopamine. This means they can mimic the way dopamine works which can reduce your symptoms.
Name some dopamine receptor agonist
Pramipexole, ropinirole; rotigotine (transdermal patch)
Which medication is most effective and has the least effects for parkinsons ?
L-dopa
What medication may be preferred in early disease if low motor dysfunction
DA or MAO-B