Gastric secretions Flashcards
1
Q
What are the two types of antcaids ?
What is a common side effect with them ?
A
1- Magnesium salts - Diarrhoea
2- Aluminium salts - Constipations
1
Q
What medications can influence acid secretions (5)
A
-Antacids
-histamine 2 antagonists,
-Proton pump inhibitors
- triple therapy, which includes antibiotics and mucosal protectants.
2
Q
Name a Histamine H2 antagonist
How does it work ?
A
Famotidine
Competitive inhibitor of H2 receptor in parietal cell, reduces histamine-induced cAMP↑ stimulation of the proton pump
3
Q
Name a PPI
How does it work
A
Omeprazole
Irreversible inhibition of H/K ATP-ase which prevents gastric secretion.
4
Q
What is the triple therapy used for H.Pylori infections?
A
1- PPI
2- Clarithromycin
3 - Metronidazole OR Amoxicillin
