Parkinson Flashcards
Abnormality of degeneration of the dopaminergic neurons
Parkinson’s dse
Where are dopaminergic neurons mainly found?
Substantia nigra pars compacta
Parkinson’s dse ia a symptom under what condition?
Parkinsonism
Clinical manifestations of patients with Parkinsonism syndrome
Tremors
Rigidity
Bradykinesia
Classifications of Parkinsonism
Primary
Secondary
Parkinson’s plus syndrome
Heredo-degenerative
Another name for primary or idiopathic parkinsonism
Paralysis agitans
Most common type of secondary parkinsonism
Vascular PD
Parkinson plus syndrome diseases
dse c rigidity, bradykinesia, and tremors + lewy body dementia
dse c rigidity, bradykinesia, and tremors + parkinson syndrome s upward/downward gaze (progressive supranuclear palsy)
Heredo-degenerative parkinsonims presents with
Kernicterus
Honeymoon period
0-3 years
Motor complication period
3-8 years
Resistant symptoms
8-15 years
Cognitive decline period
20-death
Condition of pt in honeymoon period
Very good response
Condition of pt in motor complication period
Often does not have response
Conditions of pt in resistant symptoms
Usually severely disabled at this stage
Condition of pt in cognitive decline period
Dementia may occur
