Parasites Intro Flashcards

1
Q

obligate v facultative parasites

A

obligate can’t live outside (Ascaris Lumbricoides)

facultative- can grow free living as well as in host ( stronglyloides)

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2
Q

endoparasite

A

parasite the lives inside host

leishmania

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3
Q

ectoparasite

A

lives outside of host (phtrhus pubis)

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4
Q

definitive hosts

A

hosts in which a parasite reaches sexual maturity and reproduces ( malaria mosquito– for schistosome mansoni)

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5
Q

intermediate hosts

A

host in which some development of parasite occurs but doesn’t mature
(boar– trichinella spirals)

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6
Q

reservoir host

A

animals that harbor a species of parasite that is infective for humans
(armadillo- trypanosome cruzi)

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7
Q

vector host

A

arthropod or other carriers that transport pathogenic parasite from infected to non infected host
(Aedes Aegypti)

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8
Q

dead end host

A

organisms that harbor intermediate life stage BUT do no transmit parasite to another host
(Dirofilaria minis, heart worm)

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9
Q

I. protozoan size and movement

A

unicellular organisms, 1 micron– 100 microns
locomotion by:
- flagella-
-cilia- hair like that also serve as organelles
- pseudopodia: temporary projections of cytoplasm used for ingestion of food and locomotion
or undulating membranes

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10
Q

protozoal GI and membranes

A

outer cell membrane controls fluid and food uptake

cytoplasm consists of a thin ectoplasm (where digested particles are extruded) and a thick endoplasm

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11
Q

protozoan nucleus

A

has outer nuclear membrane inner reticulum
chromatin
karyosome (tight amount of dna)

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12
Q

function of endoplasm in protozoa

A

nutrition

contains food vacuoles, reserves and foreign bodies

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13
Q

function of contractile vacuoles in protozoa

A

regulate osmotic pressure and eliminate waste materials

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14
Q

protozoan Sex

A
  • asexual- binary fission
  • asexual- multiple fission (schizogony)
  • asexual - internal budding (endodyogeny)
  • sexual- fertilization (syngamy)
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15
Q
II. Flat worms (class Trematodes)
size and morphology
A

flattened elongated leaf like
schistozosomes - ovoid and cylindrical

1-5 cm
they have a non cellular integument that has spines and tubercles

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16
Q

body of trematodes

A
  • they have suckers or spines that used for attachment of host
    don’t have a body cavity
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17
Q

trematode life cycle always includes?

A

SNAILS as an intermediate host

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18
Q

trematode sex

schistosome sex?

A

Hermaphroditic!- Ovaries and testes present in each individual

eggs are released into body cavity of host

schistosomes– dioecious- either ovaries or sperm

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19
Q

III, Cestodes – tapeworms

body

A

ribbon like segmented and inhabit intestinal tract

microvillus like structures make it continuous from one segment to another - body wall is an active tegument

20
Q

cestodes

    • scolex
    • proglotid
    • strobilus
A

scolex- anterior attachment organ
proglotid- segments
strobila- chain of segments

21
Q

sex of cestodes

A

HERMAPHRODITIC

each proglottid has reproductive organs that allow self fertilization- each one is considered a reproductive unit

22
Q

larva of cestodes

A

mature- inhabit GI tract

larva- tissues and organs (brain)

23
Q

Nematodes (round worms) body

A

1- 30 cm
stiff clear non cellular cuticle
has teeth hook and lips used for tissue abrasion or attachment

24
Q

nematode digestive sistem

A

well developed

- feed by sucking host blood or ingesting lysed tissues or GI contents - has midgut handout and anus

25
Q

how do nematodes grow

A

molting to increase body size

- these skins cause an immune response

26
Q

nematode sex

A

BOTH MALE AND FEMALE* dioecious

27
Q
  1. Arhtropods body
A

exoskeleton- external rigid tegument with chitinized membranes
3 legs0 insect
4 legs arachnids

28
Q

arthropod GI

A

forgot midgut handout rectum anus

29
Q

arthropod growth

A

molting - complete/ incomplete metamorphosis

30
Q

sex arthropods

A

dioecious
oviparious
viviparous
oviviparous- larvated eggs

31
Q

GI tract trematodes

A
  • they just have a digestive tract rather than a body cavity
    starts with a pharynx and bifurcates into two posterior tubes
32
Q

GI tract cestodes

A

absent GI tract

but their integument is enzymatically active = so they absorb their host food

33
Q

non specific host resistance to parasites

A

chemical barriers
physical barriers
microbial antagonism– anti parasitic factors in serum and competition of nutrients by normal flora

34
Q

pathological changes caused by parasites

A
  • parenchymatous degeneration
  • fatty degeneration
  • necrosis
  • hyperplasia
  • hypertrophy
  • metaplasia
  • neoplasia
35
Q

parenchymatous degeneration

A

damage to cells- characterized by swollen cells packed with fatty granules, indistinct nuclei and pale cytoplasm (washed out)

liver heart kidney

36
Q

fatty degeneration

A

deposition of large amounts of fat in cells- yellowish color

37
Q

necrosis

A

death- gives an opaque appearance

38
Q

hyperplasia v hypertrophy

A

hyperplasia increase in cell number due to accelerated cell division (due to an increase in body repair activity due to inflammation)
hypertrophy increase in cell size

39
Q

metaplasia

A

conversion of one tissue into another without intervention of embryonic tissue

40
Q

neoplasia

A

abnormal cell growth- producing an entirely new cell structure

41
Q

lab diagnosis of parasites

A
  • fecal concentration
  • trichrome stain
  • acid fast stain
  • KOH
  • Giemsa
  • wrights
42
Q

fecal concentration test

A

use of flotation (bc parasite eggs float in zinc sulfate solutions of high osmolarity)

so they are picked up and observed

43
Q

trichrome stain

A

stain parasites in fecal matter- stain protozoans cells pink with blue green organelles

44
Q

acid fast stain

A

stance cells pink with a blue background

45
Q

KOH preparatun

A

for presence of arthropods and parasites

tissues dissolve away leaving the clinical specimens

46
Q

giemsa stain

A

looking for intracellular structures

blue colored intracellular parasites

47
Q

wright stain

A

for identification of cell types in blood smears