Paper 3 Schizophrenia Flashcards

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1
Q

Describe positive symptoms of SZ and give an example

A

Symptoms that add something to your life
EG- hallucinations

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2
Q

Describe negative symptoms of SZ and give an example

A

Symptoms that reduce your normal function
EG avolition-lack of motivation

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3
Q

Outline what alogia is

A

Speech poverty, it becomes hard to form sentences.

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4
Q

Outline the DSM-5 as a manual for sz diagnosis

A

It is a manual for classifying schizo that requires patients to have 1 positive symptom

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5
Q

Outline a study that suggests patients are much more likely to be diagnosed using the ICD compared to the DSM

A

Cheniaux et al- suggests that ICD either diagnoses too many patients or the DSM diagnoses too little.

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6
Q

Outline the ICD as a system for SZ diagosis

A

The ICD (International Classification of Disease) requires two negative symptoms for diagnosis

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7
Q

What factors affect validity of diagnosis

A

Gender
Symptom overlap
Comorbidity

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8
Q

Outline How gender bias affect the validity of diagnosis, include a study in your answer

A

Broverman et al
Found US clinicians equated mentally healthy behaviour with male mental health

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9
Q

Outline and explain how symptom overlap affects the validity of SZ diagnosis

A

The symptoms of one disorder may overlap with those of schizophrenia
EG under the ICD they may be SZ but on the DSM they may be bipolar

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10
Q

Outline and explain comorbidity affecting the validity of SZ diagnosis, use a study to support your answer

A

It confuses diagnosis, making treatment hard

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11
Q

Outline the genetic explanation for SZ

A

The more genetically similar you are to someone with SZ, the more liekly you are to have SZ

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12
Q

Outline one study to support the genetic explanation for SZ

A

Gottesmann and Shield-
Kids who had two SZ parents had a 46% concordance rate
COMPARED TO 13% with one parent

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13
Q

What concordance rate for SZ between MZ twins was found by GOTTESMANN AND SHIELD

A

48% compared to 17% with DZ

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14
Q

Outline one study that looks into adoption and biological similarities

A

TIENARI-
In Finland and found 11/164 adoptees who had biological mothers with sz to also have SZ
COMPARED TO 4/197 IN THE CONTROL GROUP(NON SZ MOTHERS)

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15
Q

What is one problem with GOTTESMAN and SHIELDS study

A

because the conc is 48% we cannot assume that genes are the only reason for developing SZ

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16
Q

Evaluate one positive of the genetic explanation to SZ

A

It provides a back bone to diagnosis

17
Q

Name one piece of confounding research to the genetic explanationf fo SZ

A

Loehlin and Nichols-
aruge that identical twins are treated more similarly compared to non identical which means SZ may be environmental

18
Q

What model may offer a more appropriate explanation for SZ

A

Diathesis

19
Q

Outline the dopamine hypothesis for SZ

A

It states that-
-dopamine is fired too often/ easily causing SZ symptoms

20
Q

What may happen if dopamine levels arent rught

A

it may lead to hallucinations

21
Q

Explain how too much dopamine leads to positive SZ symptoms

A
22
Q

Why are SZs thought to have abnormally high levels of D2 receptors

A

SZs are thought to have more D2 receptors on recieving neurones resulting in more dopamine binding leading to more firing

23
Q

Give a piece of evidence to support the dopamine hypothesis for SZ

A

Amphetamines-stimulate nerve cells containing dopamine causing flooding-large doses can cause hallucinations and delusions

24
Q

How do antipsychotics back up the dopamine hypothesis for SZ

A

They work as ANTAGONISTS by reducing stimulation on the dopamine system, eliminating SZ symptoms

25
Q

Outline Seeman’s research into the dopamine hypothesis for SZ

A

found that SZs had increased dopamine in areas of the brain through POST MORTEMS

26
Q

Evaluate Seeman’s research into the dopamine hypothesis for SZ

A

It has high spatial validity
Low temporal resolution

27
Q

How can L-Dopa be used to support the dopamine hypothesis for SZ

A

It works on Parkinson’s by increasing dopamine, in turn it produces symptoms of SZ