Paper 2 - Biopsychology - Circadian Rhythms Flashcards

1
Q

What process has split brain patients undergone?

A

commissurotomy

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2
Q

What was the aims of Sperry’s research?

A

To investigate the hemispheric functioning of split brain patients.

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3
Q

What type of experiment was Sperry’s experiment?

A

To investigate the hemispheric functioning of split brain patients.

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4
Q

Who were the participants in Sperry’s experiment?

A

11 individuals had their corpus collosum removed to treat epilepsy

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5
Q

What was the procedure in Sperry’s experiment?

A

Pps were asked to perform a range of tasks and their performance was compared with pps with no interhemispheric disconnection. The tasks involved presenting information to one hemisphere by sending it to only one visual field. They were blindfolded so that only one eye was receiving the information
In other tasks, their hands were screened from them so they could not see objects placed in front of them i.e. an object shown to the right visual field, or placed in the right hand will only be perceived by the left hemisphere.

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6
Q

What does hemispheric lateralisation mean?

A

This is when the 2 brain hemispheres are separated by removing part of or all of the Corpus Collosum

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7
Q

What joins the 2 hemispheres?

A

The Corpus Collosum

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8
Q

What impact was there on the split brain monkey?

A

No impact on the monkey. They were accepted back as king of the colony straight away. When the monkeys were given a task to push a button to receive to retrieve a treat, when it was presented in thier right visual field they could not push the button. But they could grab food with both hands

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9
Q

When was Sperry’s investigation?

A

1968

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10
Q

What were the results of Sperry’s investigations?

A

• Visual material shown to the left hemisphere right visual field) can be described in speech and writing. If it is shown to the right hemisphere (left visual field) participants will deny seeing anything, but they are able to pick out the correct object with their left hand;
• If two different figures are shown to the hemispheres then the participant will be able to draw what they have seen in the left visual field with their left hand (right hemisphere). However, if asked what they have drawn they will tell you the object they saw in the right visual field (left hemisphere).

• An object placed in the right hand (left hemisphere) can be described and named. An object placed in the left hand (right hemisphere) cannot be described or named, but can selected from other objects.
• Objects can only be selected again by the hand in which they were horiginally placed. The left hand will ignore objects that the right hand is looking for, and vice versa. As Sperry commented, it is like two different people are completing the same task.

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11
Q

What were the conclusions of Sperry’s experiments?

A

There is some lateralisation of function between the hemispheres

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12
Q

What are the strengths of Sperry’s experiments?

A

• High levels of control
• Clearly demonstrated the lateralisation of function between the left and right hemisphere;
• Although it was a small sample, it was probably representative of the people who have had this operation;

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13
Q

What are the weaknesses of Sperry;s study?

A

• The tasks are low in ecological validity- the problems participants faced in the task would probably not be a problem in real life;
• It may not be possible to compare the brains of severe epileptics who have undergone brain surgery to the brains of ‘normal’ people;
• There were only 11 participants which is a small sample to generalise from.

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14
Q

What may the case study of Tony and Joe show us?

A

Plasticity can’t fully repair the brain

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15
Q

What does the case studies of Joe and Tony suggest about quality of life?

A

It suggests that this surgery can be used to improve quality of life. But they should always try to take out as little as possible to allow some communication. But rehabilitation is sometimes required.

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16
Q

What are the positive evaluations for split brain research?

A

It demonstrated lateralised brain functions
The methodology is good

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17
Q

What are the negative evaluations of split brain research?

A

There is theoretical bias
Issues with generalisation
Differences in function may be overstated

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18
Q

Explain the positive evaluation of split brain research: demonstrated lateralised brain functions

A

The pioneering work into the split brain phenomenon has produced an impressive and sizeable body of research findings - the main conclusion of which appears to be that the left hemisphere is more geared towards analytics and verbal tasks, whilst the right is more adept at performing spacial tasks and music

The right hemisphere can only produce rudimentary words and phrases but contributes emotional and holistic content to language

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19
Q

Generally what do the left and right hemisphere do?

A

left hemisphere - analyser
right hemisphere - synthesiser

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20
Q

Explain the positive evaluation of split brain research: Good methadology

A

Experiments use highly specialised and standardised procedures
The method used was ingenious - typically participants would be asked to stare at a given point the “fixation point” whilst one eye is blindfolded
The image projected would appear for 0.1 seconds so the participant doesn’t have time to move their eye across the image and so spread the information across both sides of the visual field and both sides of the brain
Sperry was able to develop a useful and well controlled procedure based of the original research

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21
Q

Explain the negative evaluation of split brain research: Theoretical bias

A

Puncetti (1977) he said suggested that we are already 2 minds and by removing the hypothalamus we are only emphasising the difference

In contrast some researchers argue that the 2 hemispheres form a highly integrated system and are both involved in most everyday tasks

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22
Q

Explain the negative evaluation of split brain research: issues with generalisability

A

The sample of participants is unusual
Only 11 who all had a history of epileptic seizures
It has been argued that this may have caused unique changes in the brain that may have influenced the findings
Some of the patients had more of their corpus collosum removed (some had extra tissue removed removed than others
The control group was 11 people without epilepsy, this may not have been the best control group

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23
Q

Explain the negative evaluation of split brain research: Difference in function may be overstated

A

Sperry’s research lead to overemphasises and oversimplified talk about the different hemispheres
The verbal and non verbal labels can be usefully applied to summarise the difference between the 2 hemispheres
But modern day neuroscientists would argue that the actual distinction is less clear cut and much more messy

In a neurotypical brain the 2 hemispheres are in constant communication. Most of the time either hemisphere could effectively perform a task which is normally performed by the other hemisphere when required rather than the past thought of lateralisation.

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24
Q

What are circadian rhythms?

A

Circadian rhythms are biological rhythms that have a periodicity of 24 hours. Periodicity in relation to biological rhythms is the time between one peak or maximum value and the next peak or maximum value.

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25
Q

Give some examples of circadian rhythms?

A

• Sleep-waking cycle: one period of sleep and one period of waking every 24 hours
• Core body temperatures: one peak and trough every 24 hours
• Hormone production: melatonin levels peak in the dark and are at its lowest during daylight

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26
Q

What do the photosensitive retinal ganglion cells do?

A

They are there to detect brightness in our surroundings and they then send the information to the SCN Photosensitive cells - they contribute to the regulation of the pubil size and other behavioural responses to ambient lighting conditions

27
Q

Where is the suprachiasmatic nuclei?

A

Aka the SCN is a bilateral structure located in the anterior part of the hypothalamus

28
Q

What does the SCN do?

A

It is the endogenous pacemaker of the circadian timing system and regulates most circadian rhythms in the body

29
Q

What is the bilateral structure located in the anterior part of the hypothalamus

A

suprachiasmatic nuclei or SCN

30
Q

How does an understanding of circadian rhythm help with drug treatment?

A

You can administer drugs at the times when it is most likely to be effective. Some drugs can make you sleepy so it is better to have them at night
Eg having heart attacks in the morning are more likely so you should take medication in the morning

31
Q

How much does your core body temperature change?

A

Around 2 degrees Celsius

32
Q

When are the extremes of the body tempreture

A

Lowest at 4am
Highest at 6pm

33
Q

At what temperature do we perform best at intellectually?

A

When we are warmer

34
Q

What did Folkard show in 1977?
Explain the study?

A

Folkard et al (1977) Children who were read a story in the afternoon remembered more of a story than the children who were read the story in the morning

35
Q

What did Gutpa show?

A

Gutpa (1991) - people get higher IQ scores when doing the test in the morning

36
Q

Explain Siffre’s cave study (1962)

A

He was totally isolated without access to the sun, people, a clock or a calendar
He ate and slept only when his body told him to, he tried to discover how circadian rhythms changed without life. He regularly weighed himself to adjust his body to a new sleep wake cycle.
If his weight increased he knew it was latter in the day (as we are lightest in the morning.

37
Q

What were the results of Siffre’s cave study (1962)?

A

His circadian rhythm became a 25 hour clock and he was able to wake up and go to sleep at the same time

38
Q

Explain Siffre’s cave study (1972)?

A

He spent 6 months in a cave in Texas. While he was in the cave he could ask for lighting to be turned on in the morning when he awoke, and turned off in the evening when he wanted to sleep. There was no external light source.
Siffre was in the cave for 179 days.

39
Q

What were the results of Siffre’s cave study. Results from both.

A

During this time his circadian sleep-wake cycle became longer than 24 hours. It was also inconsistent, varying between 25 and 32 hours. Compared to the 24-hour clock his days were therefore longer, and by his timing only 151 days had passed during the 6 months he was in the cave.
Siffre’s body temperature maintained a fairly consistent cycle, but extended to 25 hours rather than 24.
Siffre suffered psychologically during his time in the cave, with bouts of depression and suicidal thoughts.

These continued for some time after the study ended. These may have been due to the long period of isolation, or the disturbance to his biological rhythms but were not due to sleep deprivation because he could sleep whenever he liked.

40
Q

What were the conclusions from Siffre’s cave study in 1962

A

Siffre’s study shows us that the circadian rhythm of sleep waking is maintained under conditions where there are no exogenous zeitgebers. However, it is not perfectly regulated, as it becomes longer than 24 hours. This strongly suggests that the basic rhythm is controlled by an exogenous zeitgeber, light, in order to be perfectly synchronised with the day-night cycle.
The fact that the rhythm of Siffre’s body temperature became uncoupled from the sleep-wake cycle also suggests that there must be at least two body clocks, one for the sleep-wake cycle and one for body temperature. In fact, it is now known that in the body there are hundreds of body clocks involved in regulating the circadian rhythms of a variety of physiological processes.

41
Q

Which study supports Siffre’s study?

A

Aschoff et al. (1976)

42
Q

What did Folkard research?

A

He researched if Circadian Rhythms can’t easily be overridden by external environment

43
Q

What was the method of Folkard’s study?

A

He isolated 12 participants rom natural light for 3 weeks (dark cave) manipulating the clocks so that only 22 hours passed p[er day

44
Q

What were the conclusions of Folkard’s study?

A

None of the Ps could adjust comfortably to the pace of the clock (except 1)
This shows that the strength of the circadian rhythms as a free running cycle and questions the extent to which is can be overidden by exogenous zeitgebers

45
Q

What are the evaluations of Folkard’s study?

A

it is difficult to generalise the findings from studies of the sleep/wake cycle because individual cycles can vary, in some cases from 13-65 hours

46
Q

What do you need to know about breast milk?

What effect does this have on babies that are formular fed

A

Melatonin is secreted in breast milk but it varies throughout the day to help a baby know when to sleep or wake

Babies who are formula fed find it harder to regulate their sleep

47
Q

What is lateralisation of the brain function?

A

This is the process of which 1 area of the brain is responsible for a certain action

48
Q

Does the body make and keep its own circadian rhythms?

A

Yes- through the SCN and social cues such as light.

49
Q

Do circadian rhythms affect body function and health?

A

Yes for example, cancer snd chd can be effected by this

50
Q

How are circadian rhythms related to sleep?

A

It releases melatonin when the photosensitive cells detect less light which makes us tired

51
Q

How are circadian rhythms related to jet lag?

A

When we move through time zones quickly our internal body clock is off. So we rely on Exogenous zeigebers to reset our internal body clock

52
Q

What is localisation of cortical function?

A

The idea that certain areas of the brain are responsible for different functions

53
Q

What is lateralisation of cortical function?

A

The idea that some functions are controlled by a particular hemisphere

54
Q

How does the body make and keep its own circadian rhythms?

A

Trough the SCN and environmental cues such as light.

55
Q

What are EZs?

A

Exogenous zeitgebers.
External factors that influence circadian rhythms
They help process primary informations such as light through the process of photo entrainment

56
Q

What is photo entrainment?

A

The process through which EZs are used to help set the circadian rhythms through light influencing the SCN

57
Q

Ive an example of EZs?

A

Light

58
Q

What was the only difference between Siffre in 1962 than 1972?

A

In 1972 the only difference was that his sleep wake cycle increased by 1 hours. However he was still able to create a sleep schedule

59
Q

Corpus callosum stuff: Joe

A

He had to have his corpus callosum severed due to a medical condition. His brain was able to create new pathways and compensate for damaged tissue. (He was an older man)

60
Q

Corpus callosum stuff: Toney

A

Born without a corpus callosum,
He was unable to socialise
Showed little emotion
All suggesting no intra specific communication within his hemispheres.

61
Q

Explain Aschoff’s study?

A

Ppts were placed in a WW2 bunker for 4 weeks with no natural light
They settled into a sleep wake cycle of between 24 and 25 hours (apart from 1 which extended to 29 hours)

62
Q

What are the disadvantages of Aschoff and Siffre’s studdies?

A

Extraneous variable - they used artificial light and had scheduled, meal times
Confounding variables - health history
A lot of studies in this area are done on animals so they can’t be generalised (the hamster studies link to EPs and EZs.)

63
Q

What did Siffre and Aschoff agree on?

A

Natural light is the main EZ in the sleep wake cycle.