Paper 1 Exam Questions Flashcards
the movement of Na+ ions out of a cell alllows the absorption of glucose into the cell lining the ileum. explain how
2 marks
- maintains a concentration gradient for Na+
- Na+ moving in via facilitated diffusion
Describe and explain two features you would expect to find in a cell specialised for absorption.
2 marks
- microvilli so large surface area soa greater amount of substance can be absorbed at one time
- large no. of mitochondria so make more ATP
Describe how amino acids join to form a polypeptide so there is always NH2 at one and and COOH at the other end.
2 marks
- one NH2 group joins to COOH group to form peptide bond
- so there is a free amine group at one end and a free COOH group at the other
Describe the role of micelles in the absorption of fats into the cells lining the ileum.
3 marks
- micelles make fatty acids more soluble in water
- bring fatty acids to cell
- maintain high concentration of fatty acids to cell
Describe the role of DNA polymerase in the semi-conservative replication of DNA.
2 marks
- Joins (adjacent DNA) nucleotides
- (Catalyses) condensation (reactions)
Describe how an enzyme can be phosphorylated
2 marks
1.phosphate is attached to the enzyme
2. released from hydrolysis of ATP
Name three differences between DNA in the nucleus of a plant cell and DNA in a prokaryotic cell.
3 marks
plant:
histones
linear
no plasmids
prokaryotic:
no histones
cicrular
plasmids
Define non-coding base sequences and describe where the non-coding multiple repeats are positioned in the genome.
2 marks
- DNA that does not code for protein
- (Positioned) between genes;
Describe how mRNA is formed by transcription is eukaryotes.
5 marks
- Hydrogen bonds (between DNA bases) break
- One DNA strand acts as a template
- (Free) RNA nucleotides align by complementary base pairing
- RNA polymerase joins (adjacent RNA) nucleotides;
- (By) phosphodiester bonds between adjacent nucleotides
- Pre-mRNA is spliced (to form mRNA)
Describe how a polypeptide is formed by translation of mRNA
6 marks
- mRNA attaches to ribosomes
- tRNA anticodons bind to complementary mRNA codons
- tRNA brings a specific amino acid
- amino acids join by peptide bonds
- with the use of ATP
- tRNA released
- the ribosome moves along the mRNA to form a polypeptide
Define gene mutation and explain how a gene mutation can have:
- no effect on an individual
- a positive effect on an individual
4 marks
- Change in the nucleotide (sequence of chromosomes/DNA)
- Results in the formation of new allele
no effect: 3. Genetic code is degenerate
positive effect: 4. Results in change in polypeptide that positively changes the properties (of the protein)
Describe the induced fit model of enzymes action and how an enzyme acts as a catalyst
3 marks
- substrate binds to enzymes active site
- active site changes shape so it is complementary to substrate
- enzymes reduce activation energy
Explain the advantage for larger animals of having a specilaised system that facilitates oxygen uptake
2 marks
- bigger organisms have smaller SA:vol
- so faster diffusion
Explain how the counter-current principle allows efficient oxygen uptake in the fish gas exchange system
2 marks
- water and blood flow in opposite directions
- concentration gradient maintained along length of the lamellea
Describe how one amino acid is added to a polypeptide that is being formed at a ribosome during translation
3 marks
- tRNA brings specific amino acid to ribosome
- tRNA anticodon binds to mRNA codon
- amino acid joins by condensation reaction
Describe two precautions a student should take when clearing away after a organ dissection
2 marks
- Wash sharp instruments by holdng the handle
- Disinfect instruments/surfaces;
- Disinfect hands
Describe how a sample of chloroplasts could be isolated from leaves
4 marks
- Break open cells and filter
- In cold, isotnoic, pH controlled solution;
- Centrifuge and remove nuclei
- Centrifuge at higher speed, chloroplasts
settle out
Give the order of the stages of mitosis
1 mark
prophase
metaphase
anaphase
telophase