Pancreatic cancer Flashcards
1
Q
Most common type of pancreatic cancer
A
Adenocarcinoma (85%)
Other exocrine cancers (14%)
Neuroendocrine tumours (1%)
2
Q
Risk factors for pancreatic cancer
- Non-modifiable (3)
- Modifiable (4)
A
- Age >65
- Family history
- Hereditary conditions (Peutz-Jeghers, dysplastic naevus, Lynch, FAP)
- Smoking
- Obesity
- Diabetes
- Chronic pancreatitis
3
Q
Most common site of pancreatic adenocarcinoma
A
Head
4
Q
Microscopic appearance of pancreatic adenocarcinoma
A
- Poorly differentiated glands
- Desmoplasia with fibrous stroma, various cell types and deposits
5
Q
Symptoms of pancreatic cancer (7)
A
- Weight loss
- Loss of appetite
- Abdominal or back pain
- Jaundice/pale stools/dark urine
- Steatorrhoea
- Fullness/nausea
- Constipation
6
Q
Signs of pancreatic cancer (2)
A
- Courvoisier’s
- Trosseau sign of malignancy (thrombophlebitis)
7
Q
Blood tumour marker for pancreatic cancer
A
CA19-9
8
Q
Imaging for pancreatic cancer
A
- Endoscopic US
- CT
9
Q
Five-year survival rate of pancreatic adenocarcinoma
A
5%
