Pancreas Flashcards
arterial supply to pancreas
splenic artery
SMA - superior pancreaticoduodenal
IMA - inferior pancreaticoduodenal
dorsal pancreatic artery
beta cells secrete
insulin
alpha cells secrete
glucagon
delta cells secrete
somatostatin
causes of acute pancreatitis
Idiopathic Gallstones Ethanol Trauma Steriods Mumps Autoimmune Scorpion bite Hypercalcaemia, hyperlipidaemia, hyperparathyroidism ERCP Drugs
how does CBD obstruction cause acute pancreatitis
CBD obstruction causes bile to back up into pancreas and stimulate pancreatic enzyme precursors, autodigestion
fluid shift and fat necrosis causes hypocalcaemia and hypovolaemic shock
retroperitoneal haemorrhage from blood vessel digestion
acute renal failure from necrosis causing toxic metabolites to enter blood
what is cullens sign
oedema and bruising to umbilicus
what is grey turners sign
brising to flank
complications of acute pancreatitis
psedocyst abscess necrosis ascites pleural effusion renal failure shock metabolic acidosis hyperglycaemia hypocalcaemia MODS
cause of chronic pancreatitis
alcohol idiopathic PD obstruction autoimmune CF A-1-ATD Nutritional deficiency
complications of chronic pancreatitis
ascites pseudoaneurism pleural effusion splenic vein thrombosis pancreatic cancer pseudocyst biliary obstruction duodenal obstruction
most pancreatic cancers are ___
adenocarcinoma