PANCREAS Flashcards

1
Q

oq ocorre com a insulina e com o glucagon na pancreatite?

A

ambos reduzem

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2
Q

tto fistula pancreatica

A

dieta zero por 14-21 dias + NPT + Octreotide (analogo da somatostatina)

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3
Q

tumor endocrino mais comum

A

insulinoma
(pode conter triade da hipoglicemia - triade de Whipple:
-sintomas e sinais de hipoglicemia
-glicose plasmática de 45 mg/dL (2,5 mmol/L) ou menor
-reversibilidade dos sintomas com a administração de glicose

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4
Q

causas de pancreatite aguda

A
litiase biliar
alcool
hipertrigliceridemia>1000
pos CPRE
Trauma (criancas)
auto-imune: aumento do IgG4
Escorpiao
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5
Q

clinica pancreatite aguda

A

dor continua em barra/em faixa/em cinturao
epimesogastrica que irradia p o dorso
nauseas e vomitos
ictericia leve
sinais semiologicos (Cullen, Grey Turner -> indicam gravdidade, nao sao patognomonicos)

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6
Q

diag pancreatite aguda

A
2 dos 3:
- dor abdominal fortemente sugestiva
- aumento de enzimas ≥ 3x LSN
VR: amilase 160/ lipase 140
obs: grandes elevacoes nao indicam gravidade
- exames de imagem caracteristicos
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7
Q

imagem pancreatite aguda

A

1o: USG (mostra a principal causa: litiase)
definitivo: TC com contraste em 48-72h de evolucao/ se grave ou piorando

se suspeita de microlitiase: USG endoscopica

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8
Q

captacao homogenea na TC

A

Pancreatite edematosa

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9
Q

captacao necrosante na TC

A

Pancreatite necrosante

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10
Q

prognostico pancreatite aguda

A
RANSON ≥ 3
BALTHAZAR (TC)≥ 6
APACHE II ≥ 8
PCR ≥ 150
ATLANTA, BISAP, SOFA...
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11
Q

tto pancreatite aguda

A

1) medidas gerais:
- dieta zero, hidratacao e controle eletrolitico
- analgesia com opioides

2) reiniciando a dieta
- quando? fome, reducao da dor, reducao da PCR
- preferir via enteral: VO (se n tolerar: cateter NG/NJ)
- NPT se nao tolerar cateter

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12
Q

causa mais comum de pancreatite cronica

A

ALCOOL

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13
Q

triade classica pancreatite cronica

A

esteatorreia + diabetes + calcificacao pancreatica

outros achados: dor abd, emagrecimento, ictericia

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14
Q

diag pancreatite cronica

A

gordura fecal<200
USG endoscopica (fase inicial)
TC
CPRE se contraindic TC/RNM ou se for operar

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15
Q

tto clinico pancreatite cronica

A
cessar etilismo/tabagismo
dieta pobre em gordura
enzimas pancreaticas + IBP
analgesia escalonada: AINE-> amtriptilina->opioide
insulina
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16
Q

qm deve operar?

A

dor clinicamente intratavel

17
Q

epidemio CA pancreas

A

homem, idoso, negro
mutacao K-ras, p53
marcador: CA 19-9 (nao se usa p screening, indica prognostico)

18
Q
ictericia colestatica veridica
sinal de Corvisier-Terrier (vesicula indolor e palpavel)
perda ponderal
dor abdominal
linfonodo supraclavicular esquerdo
A

tumor de cabeca de pancreas (periampular)