Palliative care

Question 1

Antiemetic for reduced gastric motility

Answer 1

Metoclopramide or domperidone

Don’t use metoclopramide in complete bowel obstruction, GI perf or following GI surgery

Question 2

Antiemetic for chemically mediated N&V

Answer 2

Correct chemical disturbance if possible
Ondansetron (especially for chemo), haloperidol, levomepromazine

Question 3

Antiemetic for visceral/serosal causes (e.g. constipation, oral candidiasis)

Answer 3

Cyclizine and levomepromazine

Question 4

Antiemetic for raised intra-cranial pressure

Answer 4

Cyclizine
Dexamethasone

Question 5

Antiemetic for vestibular causes

Answer 5

Cyclizine
Refractory - metoclopramide, prochlorperazine

Question 6

Antiemetic for cortical causes (e.g. anxiety, pain, fear, anticipatory nausea)

Answer 6

Anticipatory nausea then short acting benzo e.g. lorazepam
Cyclizine