Neurology Flashcards

1
Q

What is Horner’s syndrome

A

Ptosis, miosis and anhidrosis
Oculosympathetic paresis (disruption of sympathetic nerve supply to eye)

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2
Q

What is Argyll-Robertson pupil

A

Pupils accommodate but don’t react to direct or consensual light stimulation
Primarily in neurosyphilis

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3
Q

How does third nerve palsy present

A

Ptosis, mydriasis and ‘down + out’ deviation of eye

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4
Q

What is Holmes-Adie pupil

A

Unilateral dilated pupil that reacts poorly to light and slow constriction on accommodation
Associated absent reflexes e.g. ankle jerk

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5
Q

Features of motor neuron disease

A

Asymmetric limb weakness - most common presentation of ALS
Mixture of upper and lower motor neuron signs
Wasting of the small hand muscles/tibialis anterior
Fasciculations
Absence of sensory signs/symptoms
Doesn’t affect external ocular muscles
No cerebellar signs
Abdominal reflexes usually preserved and sphincter dysfunction is late feature if present

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6
Q

Management of carpal tunnel syndrome

A

6 week trial of conservative treatments if mild-moderate symptoms - corticosteroid injection, wrist splints at night
Severe symptoms or persisting then surgical decompression

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7
Q

Anterior cerebral artery stroke symptoms

A

Contralateral hemiparesis and sensory loss - more in lower limbs

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8
Q

Middle cerebral artery stroke symptoms

A

Contralateral hemiparesis and sensory loss - more in upper limbs
Contralateral homonymous hemianopia
Aphasia

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9
Q

Posterior cerebral artery stroke symptoms

A

Contralateral homonymous hemianopia with macular sparing
Visual agnosia (unable to recognise images)

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10
Q

Weber’s syndrome (branches of posterior cerebral artery that supply midbrain)

A

Ipsilateral CN III palsy
Contralateral weakness of upper + lower extremity

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11
Q

Posterior inferior cerebellar artery stroke (aka Wallenburg syndrome/lateral medullary syndrome) symptoms

A

Ipsilateral facial pain and temp loss
Contralateral limb/torso pain and temp loss
Ataxia, nystagmus

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12
Q

Anterior inferior cerebellar artery stroke (lateral pontine syndrome) symptoms

A

Ipsilateral facial paralysis and deafness

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13
Q

Basilar artery stroke symptoms

A

Locked in syndrome

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14
Q

Cluster headache management

A

Neurology referral
Acute - 100% oxygen, subcut triptan
Prophylaxis - verapamil

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15
Q

MS features

A

Visual:
- Optic neuritis - common
- Optic atrophy
- Uhthoff’s phenomenon - worsening of vision following rise in body temp
- Internuclear ophthalmoplegia

Sensory:
- Pins/needles
- Numbness
- Trigeminal neuralgia
- Lhermitte’s syndrome - paraesthesia in limb on neck flexion

Motor:
- Spastic weakness - most commonly legs

Cerebellar:
- Ataxia
- Tremor

Other:
- Urinary incontinence
- Sexual dysfunction
- Intellectual deterioration

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16
Q

Essential tremor

A

Autosomal dominant
Worse if arms are outstretched
Improved by alcohol and rest

17
Q

Essential tremor management

A

Propranolol first line
Primidone

18
Q

Trigeminal neuralgia management

A

Carbamazepine

Failure to respond to treatment or atypical features then refer to neuro

19
Q

Guillain-Barre presentation

A

Progressive, symmetrical weakness of limbs
Ascending weakness
Reduced or absent reflexes
Very few sensory signs

20
Q

Guillain-Barre investigations

A

LP - rise in protein with normal WCC
Nerve conduction studies:
- Decreased motor nerve conduction velocity
- Prolonged distal motor latency
- Increased F wave latency

21
Q

Myasthenia gravis presentation

A

Muscle fatigue especially after exercise and ocular manifestations - droop of upper eyelids with weakness of external ocular muscles causing diplopia

Normal reflexes, normal tone, sensation fine

22
Q

Polymyositis presentation

A

Diffuse weakness in proximal muscles
Weakness varies from week to week

23
Q

Acute transverse myelitis presentation

A

Acute episode of weakness or paralysis of both legs, with sensory loss + loss of control of bowels and bladder
Associated back or leg pain