Dermatology

Question 1

Which conditions are associated with pyoderma gangrenosum

Answer 1

IBD, RA, SLE
Myeloproliferative disorders, lymphoma, myeloid leukaemias, monoclonal gammopathy
Granulomatosis with polyangiitis
Primary biliary cirrhosis

Question 2

Pyoderma gangrenosum features

Answer 2

Usually on lower limb
Often at site of minor injury
Skin breaks down to form ulcer
May have systemic symptoms e.g. fever, myalgia

Question 3

Pyoderma gangrenosum management

Answer 3

Steroids
May need other immunosuppressive therapy e.g. ciclosporin, infliximab

Question 4

Erythema multiforme

Answer 4

Target lesions
Hypersensitivity reaction usually triggered by infections or drugs

Question 5

Bullous pemphigoid

Answer 5

Autoimmune condition causing sub-epidermal blistering of skin
Itchy

Question 6

Erythema marginatum

Answer 6

Reactive inflammatory erythema from rheumatic fever (rare)
Barely raised lesions

Question 7

Erythema nodosum

Answer 7

Inflammation of subcutaneous fat causing tender erythematous nodules on shins
Triggered by infection or systemic disease e.g. sarcoidosis

Question 8

Stevens-Johnson syndrome

Answer 8

Severe systemic disease affecting skin and mucosa
Almost always caused by a drug reaction
Maculopapular rash with target lesions, and blistering and peeling of skin
Feel systemically unwell with fevers and arthralgia

Question 9

Pemphigus vulgaris

Answer 9

Autoimmune blistering disorder with intra-epidermal blisters
Bullae easily rupture leaving painful erosions

Question 10

Erythema multiforme major

Answer 10

Systemic symptoms with mucosal involvement

Question 11

Scalp psoriasis management

Answer 11

First line - topical potent steroid e.g. betamethasone valerate
Second line - topical vitamin D

Question 12

Alopecia areata management

Answer 12

Topical or intralesional steroids
Topical minoxidil
Phototherapy
Dithranol
Contact immunotherapy