Palliative Flashcards

1
Q

Break through pain relief

A

1/6th of overall used

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2
Q

How much to increase opioids by

A

30-50%

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3
Q

Converting codeine to morphine

A

/10

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4
Q

Converting tramadol to morphine

A

/10

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5
Q

Converting morphine to oxycodone

A

/2

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6
Q

PO 30mg morphine to a fentanyl patch

A

12mcg fentanyl patch

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7
Q

PO 24mg morphine to buprenorphine patch

A

10 mcg buprenorphine patch

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8
Q

PO morphine to SC morphine

A

/2

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9
Q

PO morphine to SC diamorphine

A

/3

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10
Q

PO oxycodone to SC diamorphine

A

/1.5

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11
Q

Pancreatic cancer pain relief

A

Can use coeliac plexus block

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12
Q

Gabapentine MOA

A

Binds to the alpha subunit of voltage gated calcium channels

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13
Q

Anti emetics used in Parkinsons

A

Cyclizine (can use ondansetron but this can cause constipation)

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14
Q

Aprepriant moa

A

neurokinin 1 (anti-emetic), inhibits substance P

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15
Q

Lorazepam MOA

A

GABA A modulator

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16
Q

Baclofen MOA

A

GABA B modulator

17
Q

Can steroids cause hallucinations

A

Yes!

18
Q

How often should you change a syringe driver

A

24 hourly
(note should monitor syringe driver site every 4 hours)

19
Q

Morphine and midazolam can they be in the same syringe driver

A

Yes

20
Q

Hypercalcaemia antiemetic of choice

A

Haloperidol

21
Q

Intracranial pathology antiemetic of choice

A

Cyclizine

22
Q

Chemotherapy antiemetic of choice

A

Ondansetron is first line, lorazepam is second choice

23
Q

Oxaliplatin use

A

Folinic acid and 5-FU used for metastatic colorectal carcinoma

24
Q

How long does it take for a syringe driver to start working

A

3-4 hours

25
Q

Opioid induced constipation management

A

Senna –> sodium docusate

26
Q

First line agent in constipation in palliative care

A

Lactulose