Oncology Flashcards

1
Q

Ca19-9

A

Pancreatic

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2
Q

CEA

A

Colorectal

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3
Q

HNPCC caner

A

Colorectal and endometrial

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4
Q

AFP

A

Liver, testicular

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5
Q

Chromogranin A

A

Carcinoid (bronchial carcinoid tumour)

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6
Q

Carcinoid tumour management

A

Ocreotide

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7
Q

SIADH is associated with which malignancy

A

Small cell

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8
Q

Small cell cancer chemo agents

A

Cisplatin and etoposide

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9
Q

Non small cell cancer chemo agents

A

Carboplatin and paclitaxel

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10
Q

Cancer that kills most women in the UK

A

Lung

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11
Q

Most common cancer in the UK for women

A

Breast

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12
Q

Oesophageal adenocarcinoma histology

A

Tubo-papillary growth

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13
Q

Ca153

A

Breast

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14
Q

Ca125

A

Ovarian

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15
Q

Vinyl chloride

A

Haemangiosarcoma of the liver

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16
Q

Nickel

A

Cancer of the oral cavity

17
Q

Arsenic

A

Skin cancer

18
Q

EBV

A

Lymphoma - Hodgkins and Burkitts

19
Q

Human herpes virus 8

A

Kaposi’s sarcoma

20
Q

Human T lymphocyte virus

A

Leukaemia

21
Q

Hepatitis B

A

Liver

22
Q

Lymphoma investigation

A

Excisional biopsy (not FNB as can miss cancer cells)

23
Q

Paraneoplastic cerebellar degeneration antibody

A

anti-Yo

24
Q

Why is HCC more common in China

A

Large number of hepatitis B patients

25
Q

Burkitts lymphoma

A

c-MYC
starry sky

26
Q

What is CEA used for

A

Post op surveillance colon cancer

27
Q

Blood film finding for a patient with prostate cancer

A

Leukoerythroblastic picture

28
Q

Which side varicocele in renal cancer

A

LHS

29
Q

Imatininb moa

A

Tyrosine kinase inhibitor

30
Q

How do SCC spread

A

Lymphatics

31
Q

Which cancers respond well to imatinib

A

GIST and CML

32
Q

Phase I trial

A

Looks at human toxicity and pharmacokinetics

33
Q

Phase II trial

A

Establish anti-tumour effet of drug

34
Q

Phase III trial

A

Compares new drug to best conventional therapy

35
Q

Phase IV trials

A

Look at long term effects of drug

36
Q

What does R mean in cancer staging

A

Residual volume of cancer left

37
Q

Non invasive bladder cancer treatment

A

TURBT and mitomycin C (if muscle invasive can give BCG)q

38
Q

Which part of the cell cycle are cells least likely to respond to chemo

A

G0

39
Q

Chronic gastritis, type of cancer related

A

MALT lymphoma