Pain + Thermo-sensation Flashcards
what is nociceptive?
pin prick sensation
where is nociceptive cell bodies located?
dorsal roots of trigeminal ganglia
what are the 2 types of fibres found?
Alpha delta and C fibers
how many types of alpha delta fibres are there?
2
what is type 1 alpha delta activated by?
heat
what kind of receptors do type 1 alpha delta have?
high threshold mechanoreceptors –> slow sensation
what do alpha delta type 2 fibres respond to?
noxious stimuli - harmful/unpleasant
what is alpha delta type 2 fibres sensitive to?
capsaicin - sensation of burning
what do all c fibres respond to?
all noxious stimuli
what is the function of C-MH?
c fiber - detects mechanical stimuli by being activated by noxious heat
able to locate exact location of stimuli
what is the function of C-M?
mechanical stimuli but insensitive to heat + capsalcin
what is the function of C-H?
sensitive to capsalcin + mediates heat detection but does not contribute to location of stimuli
what is the function of C-MH (silent)?
insensitive to heat or mechanical pain
sensntive to capsalcin + other analgesia
what are the 2 terminals involved in signalling of noiceptors?
central and peripheral terminals
what does the central terminal cause?
hyperalgesia