Introduction to Nerve Conduction Flashcards
What is the function of dendrites?
receive inputs from other neurones + convey graded electrical signals to stoma
what is the axon hillock?
site of invitation of ‘all or nothing’ law
what is the major excitatory neurotransmitter?
glutamate
what is the name of the receptor that glutamate acts upon?
NDMA/Non-NDMA
What results in glutamate binding onto non-NMDA receptor sites?
bines agonists which controls Na+/K+ synapses –> mediates fast excitatory
What results in glutamate binding onto NMDA receptor sites?
promotes neurotoxicity –> slow component e.g. ketamine
What is the name of the neurotransmitter that is released in small packages?
QUANTA
What is the main inhibitory neutrotransmitter?
GABA
What are the 2 potential receptors that GABA could bind to?
ionatropic GABAa
metabotropic GABAb
What does GABAa control?
Cl-
What does GABAb control?
K+
What does EPSP mean?
Excitatory post-synaptic potential
What does IPSP?
Inhibitory post synaptic potential
Give an example of a drug which binds onto GABAa?
Benzodiazepines
Give an example of a drug which binds onto GABAb?
Baclofen