Pain Reliever Drugs Flashcards
What are the uses of Carprofen?
It is used primarily in dogs for osteoarthritis, postop surgical pain, and most inflammatory pain.
Carprofen is known for its effectiveness in managing pain and inflammation in veterinary medicine.
What does Carprofen inhibit in the body?
It inhibits COX enzymes, mostly COX-2, leading to reduced inflammation and pain.
COX-2 is an enzyme that plays a significant role in the inflammatory process.
How is Carprofen commonly administered?
It can be administered via SQ injection, PO (most common), chewable tablets, and caplets.
PO stands for per os, meaning by mouth.
What are the most common side effects of Carprofen?
The most common side effects include:
* Diarrhea
* Vomiting
* GI ulceration/bleeding (although rare)
Monitoring for these side effects is important during treatment.
What precautions should be taken when using Carprofen?
Use with caution with prolonged use and monitor liver and kidney values. It is not approved for use in cats in the U.S.
Regular veterinary check-ups are essential for monitoring organ function.
What is the most common trade name for Carprofen?
Rimadyl
Other trade names include Novox, Vetprofen, and at least 8 more.
Fill in the blank: Carprofen is primarily used in _______.
[dogs]
What is Deracoxib also known as?
Deramaxx®
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) used for pain relief in dogs.
For which animals is Deracoxib approved?
Dogs only
This medication is specifically formulated and approved for canine use.
What are the brand names for Firocoxib?
Previcox®, Equioxx®
Firocoxib is marketed under these brand names for veterinary use.
For which animals is Firocoxib approved?
Dogs and horses
Firocoxib is versatile and can be used for both canine and equine patients.
What is Robenacoxib approved for?
Dogs and cats (only 3 days in cats)
Robenacoxib is marketed under the brand name Onsior®.
What forms does Robenacoxib come in?
Injectable and tablets
Robenacoxib is available in multiple formulations for ease of administration.
What is Meloxicam indicated for?
Dogs and cats (only 1 perioperative dose approved in cats)
Meloxicam is also known by the brand names Metacam® and Loxicom®.
What is a notable FDA warning associated with Meloxicam in cats?
FDA black box warning to avoid repeated use
This warning is not present in other countries due to decreased dosing recommendations.
What forms does Meloxicam come in?
Injectable and liquid suspension
Meloxicam’s various formulations allow for flexibility in treatment.
True or False: Robenacoxib can be used for more than 3 days in cats.
False
Robenacoxib is only approved for a maximum of 3 days in cats.
What is Grapiprant (Galliprant®)?
A newer NSAID used to treat canine osteoarthritis.
Grapiprant represents an advancement in pain management for dogs suffering from joint issues.
How does Grapiprant differ from traditional NSAIDs?
It has a different mechanism than traditional NSAIDs and is NOT a COX-inhibitor.
Traditional NSAIDs typically inhibit cyclooxygenase (COX) enzymes, which are involved in the inflammatory response.
What is the impact of Grapiprant on the liver, kidneys, and GI tracts?
It has a reduced impact on these organs compared to traditional NSAIDs.
This makes Grapiprant a safer alternative for long-term use in dogs with osteoarthritis.
What is Grapiprant approved for?
Use in dogs only, PO tablets
Grapiprant is specifically designed for canine use.
What are the side effects of Grapiprant?
Vomiting, diarrhea, decreased appetite, lethargy
These side effects may vary in severity among different dogs.
What are the contraindications for Grapiprant?
Do not use in cats
Grapiprant is not safe for feline use.
What is the trade name of Grapiprant?
Galliprant
Galliprant is the commercial name under which Grapiprant is marketed.
