Endocrine Drugs Flashcards
Levothyroxine
what is it
trade names
admin
side effects
supplemental thyroxine - tx hypothyroidism
trade: soloxine, thyro-tabs
admin PO daily for life on empty stomach
side effects rare
liothyroine sodium
why use
T3 - tx of hypothyroidism but rarely use
Methimazole
what does it treat
side effects
trade name
tx hyperthyroidism
Felimazole trade name
side effects: anorexia, V, D, skin lesions, pruritus
Radioiodine (I-131)
what does it do
concentrates in thyroid gland and destroys tissue (radioactive)
expensive as one-time tx
what is hyperadrenocorticism called
cushing dz
trilostane
trade name
what does it do
side effects
vetoryl
tx of hyperadrenocorticism (cushing)
side effects: anorexia, lethargy, weakness, v/d
mitotane
what does it tx
side effects
trade name
tx hyperadrenocorticism (cushing)
lysodren
side effects: anorexia, lethargy, v/d, eventually may become hypo-
pergolide
what does it tx
side effects
trade name
prascend
tx PPID in horses
side effects: anorexia, colic, D, weight loss, behavioral changes
leuprolide
what does it tx
adrenal gland dz in ferrets - caused reduced release of androgens over time
dexmethasone
why do we use it
hypoadrenocorticism in acute, er cases
DOCP
what is trade name
what does it treat
how to admin
hypoadrenocorticism tx
trade: percorten-V or zycortal
admin SQ-IM q25-28d
DOCP what does it do
side effects
enables electrolyte balance and fluid balance
side effects: depression, PU/PD, anorexia, v/d, incontience
fludrocortisone acetate
what does it tx
trade name
tx hypoadrenocorticism (addisons)
florinef
Fludrocortisone acetate
how to administer
side effects
PO tab
PU/PD, incontinence, hypokalemia, hypernatremia
insulin
what does it tx
what are the 2 drugs
tx diabetes
prozinc (protamine zinc) - cats only
vetsulin (procine insulin zinc) - dog and cat
SGLT2
what does it do
what are the conditions for using this drug
increase urinary glucose excretion -> more glucose is pushed out to the urine, rather then kept in the blood
P MUST BE newly-dx never on insulin
what is bexaglifoxin
trade name
admin
use
Bexacat
used to tx diabetes
PO tab
what are the side effects and contraindications of Bexaglifloxin and Velagliflozin
cats that have been treated with insulin, have hepatic dz, reduced renal function, DKA, pancreatitis
side effects: GI signs, lethargy, dehydration, weight loss, UTI, increased kidney and liver values
Velagliflozin
trade name
use
admin
Senvelgo
PO liquid
tx of diabetes
Diazoxide
tx
insulinoma
inhibits release of insulin from beta cells
Corticosteroids (pred, dexmeth)
used to tx
insulinoma tx
increase glucose in blood stream
