Pain Management Flashcards
what kind of laxatives are used with opioids
stimulant laxatives (or combo with softener)
NOT bulk forming
TCAs used as analgesics
1) amitriptyline
2) imipramine
3) desipramine
4) nortriptyline
TCAs 2ndary amines
desipramine
nortriptyline
TCAs tertiary amines
amitriptyline
imipramine
TCA AE 2ndary amines vs tertiary
secondary: fewer anticholinergic and sedative effects than tertiary
TCA precuations/contraindications
angle closure glaucoma BPH urinary retention constipation CVD impaired liver fxn
AVOID in: heart block, arrhythmias, long QT, severe liver disease, recent MI
serotonin and norepinephrine reuptake inhibitors (SNRIs) used as analgesic
venlafaxine
duloxetine
SNRI AE
nausea
sexual dysfunction
somnolence
TCA AE
anticholinergic: tachycardic, constipation, dry mouth
anticonvulsants for neuropathic pain
gabapentin
pregabalin
carbamazepine
gabapentin/pregabalin MOA
block VG Calcium channels = dec calcium influx, dec glutamate/NE/substance P release
gabapentin/pregabalin AE
dizzy
somnolence
peripheral edema
DOC for trigeminal neuralgia
carbamazepine
carbamazepine MOA
block VG Na channels
carbamazepine AE
drowsiness, n/v
carbamazepine induced leukopenia
aplastic anemia: rare