Pain Management Flashcards

1
Q

what kind of laxatives are used with opioids

A

stimulant laxatives (or combo with softener)

NOT bulk forming

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2
Q

TCAs used as analgesics

A

1) amitriptyline
2) imipramine
3) desipramine
4) nortriptyline

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3
Q

TCAs 2ndary amines

A

desipramine

nortriptyline

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4
Q

TCAs tertiary amines

A

amitriptyline

imipramine

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5
Q

TCA AE 2ndary amines vs tertiary

A

secondary: fewer anticholinergic and sedative effects than tertiary

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6
Q

TCA precuations/contraindications

A
angle closure glaucoma
BPH
urinary retention
constipation
CVD
impaired liver fxn

AVOID in: heart block, arrhythmias, long QT, severe liver disease, recent MI

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7
Q

serotonin and norepinephrine reuptake inhibitors (SNRIs) used as analgesic

A

venlafaxine

duloxetine

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8
Q

SNRI AE

A

nausea
sexual dysfunction
somnolence

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9
Q

TCA AE

A

anticholinergic: tachycardic, constipation, dry mouth

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10
Q

anticonvulsants for neuropathic pain

A

gabapentin
pregabalin
carbamazepine

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11
Q

gabapentin/pregabalin MOA

A

block VG Calcium channels = dec calcium influx, dec glutamate/NE/substance P release

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12
Q

gabapentin/pregabalin AE

A

dizzy
somnolence
peripheral edema

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13
Q

DOC for trigeminal neuralgia

A

carbamazepine

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14
Q

carbamazepine MOA

A

block VG Na channels

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15
Q

carbamazepine AE

A

drowsiness, n/v
carbamazepine induced leukopenia
aplastic anemia: rare

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16
Q

glucocorticoid DOC for pain

A

dexamethasone

17
Q

hydroxyzine as analgesic adjuvant

A

add to effect of opioids

18
Q

clonidine as analgesic adjuvant

A

may improve pain and hyperalgesia in symphathetically maintained pain

19
Q

caffeine as analgesic adjuvant

A

enhance analgesic effect of acetaminophen

20
Q

postherpetic pain patch

A

lidocaine or capsacin