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PHARM 2 > Clinical Applications of Antimicrobials > Flashcards

Clinical Applications of Antimicrobials Flashcards

1
Q

bacteriostatic or bactericidal? aminoglycosides

A

bactericidal

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2
Q

bacteriostatic or bactericidal? b-lactam

A

bactericidal

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3
Q

bacteriostatic or bactericidal? fluroquinolones

A

bactericidal

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4
Q

bacteriostatic or bactericidal? metronidazole

A

bactericidal

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5
Q

bacteriostatic or bactericidal? vancomycin

A

bactericidal

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6
Q

bacteriostatic or bactericidal? streptogramins

A

bactericidal

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7
Q

bacteriostatic or bactericidal? clindamycin

A

bacteriostatic

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8
Q

bacteriostatic or bactericidal? macrolides

A

bacteriostatic

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9
Q

bacteriostatic or bactericidal? sulfonamides

A

bacteriostatic

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10
Q

bacteriostatic or bactericidal? tetracyclines

A

bacteriostatic

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11
Q

bacteriostatic or bactericidal? trimethoprim

A

bacteriostatic

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12
Q

mode of elimination: renal/hepatic - aminoglycosides

A

renal

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13
Q

mode of elimination: renal/hepatic cephalosporins

A

renal

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14
Q

mode of elimination: renal/hepatic fluoroquinolones

A

renal

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15
Q

mode of elimination: renal/hepatic PCN

A

renal

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16
Q

mode of elimination: renal/hepatic sulfonamides

A

renal

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17
Q

mode of elimination: renal/hepatic - tetracycline

A

renal

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18
Q

mode of elimination: renal/hepatic - TMP-SMX

A

renal

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19
Q

mode of elimination: renal/hepatic - vancomycin

A

renal

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20
Q

mode of elimination: renal/hepatic - chloramphenicol

A

hepatic

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21
Q

mode of elimination: renal/hepatic - clindamycin

A

hepatic

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22
Q

mode of elimination: renal/hepatic - erythromycin

A

hepatic

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23
Q

mode of elimination: renal/hepatic - clarithromycin

A

hepatic

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24
Q

mode of elimination: renal/hepatic - nafcillin

A

hepatic

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25
Q

aerobe/anaerobe tx or both: aztreonam

A

aerobe

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26
Q

aerobe/anaerobe tx or both: aminoglycoside

A

aerobe

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27
Q

aerobe/anaerobe tx or both: metronidazole

A

anaerobe

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28
Q

aerobe/anaerobe tx or both: clindamycin

A

anaerobe

29
Q

aerobe/anaerobe tx or both: PCN G/V

A

both

30
Q

aerobe/anaerobe tx or both: carbapenems

A

both

31
Q

aerobe/anaerobe tx or both: tetracyclines

A

both

32
Q

aerobe/anaerobe tx or both: glycylcylines

A

both

33
Q

aerobe/anaerobe tx or both: chloramphenicol

A

both

34
Q

effects on neonate: aminoglycosdes

A

damage to CN 8

35
Q

effects on neonate: tetracyclines/glycylcyclines

A

tooth enamel dysplasia

inhibit bone growth

36
Q

effects on neonate: sulfonamides

A

kernicterus

37
Q

effects on neonate: chloramphenicol

A

gray baby syndrome

38
Q

effects on neonate: fluoroquinolones

A

tendon rupture/damage

39
Q

effects on neonate: nitrofurantion

A

hemolytic anemia

40
Q

effects on neonate: trimethoprim

A

folate def

41
Q

Prophylaxis: cardiothoracic

A

cefazolin
if MRSA: cefazolin + vancomyin

if PCN allergic: vancomycin + aztreonam

42
Q

Prophylaxis: colorectal

A

ampicillin, sulbactam

if PCN allergic: cipro + metro OR cipro +clindamycin

43
Q

Prophylaxis: general surgery

A

cefazolin

PCN allerg: vanco or clinda

44
Q

Prophylaxis: neurosx

A

cefazolin

PCN allerg: vanco

45
Q

Prophylaxis: orthopedics

A

cefazolin

PCN allerg: vanco or clinda

46
Q

prophylaxis: vascular

A

cefazolin or cefuroxime

PCN allerg: vanco or clinda

47
Q

C. diff tx

A

metro, vanco, fidaxomicin

48
Q

bacterial meningitis prophylaxis in adults

A

rifampin
ciprofloxacin
ceftriaxone

49
Q

yersinia pestis DOC

A

streptomycin

alt: doxycycline

50
Q

tularemia DOC

A

streptomycin

51
Q

syphillis tx in PCN allergic pt

A

doxycycline

52
Q

s. pneumo DOC

A

PCN G, amox

53
Q

s. pneumo PCN resistanct

A

3rd gen cephalosporin

fluoroquinolone

54
Q

shigella

A

ampicillin

TMP SMX

55
Q

salmonella typhi

A

ceftriaxone or fluoroquinolone

56
Q

proteus mirabilis

A

ampicillin

57
Q

nocardia

A

TMP-SMX

58
Q

n. gonorrhea

A

ceftriaxone + azithromycin

59
Q

m. pneumoniae

A

macrolide or tetracycline

60
Q

listeria

A

ampicillin

61
Q

legionella

A

fluoroquinolone or macrolide

62
Q

klebsiella

A

ceftriaxone or cefotxime

63
Q

enterobacter

A

carbapenem or cefepime

64
Q

enterococcus

A

ampicillin +/- gentamicin

65
Q

chancroid

A

azithromycin or erythromycin or ceftriaxone or cipro

66
Q

campylobacter

A

azithromycin

67
Q

brucella

A

doxyccline

68
Q

bordetella

A

macrolide

PHARM 2 (18 decks)

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