Pain

Question 1

Explain the 2 types of nociceptive pain. What kind of drugs are effective?

Answer 1

Tissue damage

Somatic: skin, mucous membranes, muscle, fasciae, bones, tendons

Visceral: internal organs

Analgesics

Question 1

Define Nociception and its 4 steps

Answer 1

Process that communicates tissue damage to the CNS

Transduction
-Noxious stimulus create action potential
Transmission
-bringing stimulus to CNS
Perception
-conscious awareness of pain involving multiple brain centers
Modulation
-body’s interpretation/response

Question 2

Explain Neuropathic pain. What drugs does it respond to?

Answer 2

Damage to peripheral nerves or CNS
-numb, hot, shooting, stabbing, burning, electrical

-trauma, inflammation, diabetes, chemotherapy-induced

-may respond to adjuvant analgesics

Question 3

Explain referred vs. radiating pain

Answer 3

Referred: location of pain reported is different from side of injury
(jaw pain with MI)

Radiating: pain travels outward from site
(left arm pain with MI)