Paget's disease/Osteitis Deformans) Flashcards
1
Q
Etiology
A
- largely unknown
- thought to be linked to a type of viral infection along with environmental factors
2
Q
what is it
A
metabolic bone disease involving abnormal osteoclastic and osteoblastic activity
- increased destruction of bone with unorganized reabsorption
3
Q
results in..
A
spinal stenosis, facet athropathy, and possible spinal fracture
4
Q
primary medial intervention
A
- drug therapy
- acetaminophen for pain
- calcitonin and etidronate disodium to limit osteoclastic activity
- biphosphonates or Pamidronate
5
Q
Diagnostic test
A
- plain film imagine
- lab tests look for increased levels of serum alkaline phosphatase and urinary htdroxyproline
6
Q
symptoms
A
- typically asymptomatic
- bone pain is typically first symptom
7
Q
what will X-rays show
A
increased bone density and enlargement
8
Q
what may be advantageous?
A
water therapy
9
Q
fractures are…
A
frequent and occur with minimal trauma
10
Q
population
A
60+ yo
men > women
11
Q
alert
A
Paget’s disease is also a type of ductal carcinoma related to breast cancer
