Paeochromocytoma Flashcards
What is phaeochromocytoma
Adrenal medullary tumour secreting Catecholamines (NAd and Adr)
What are catecholamines
NAd
Adr
What part of the adrenal gland forms a tumour in phaeochromocytoma
Adrenal medulla
What are the causes of Phaeochromocytoma
Inherited
MEN 2a and 2b
Neurofibromatosis (Myelin sheath tumour)
What are the symptoms of Paheochromocytoma
HTN
Pallor
Sweat
Tachycardia
How is Phaeochromocytoma diagnosed
Plasma = Increased Metanephrines
Why is measuring plasma metanephrines better than reading NAd/Adr
More sensitive and longer half life
What investigations can be done for Phaeochromosytoma
Plasma metanephrines
Urinary catecholamines
CT
What drugs are used to treat Phaeochromocytoma
Alpha blocker w/ beta blocker
Why are beta blockers given as well to treat phaeochromocytoma
Prevent reactive vasoconstriction
What is the definitive treatment of phaeochromocytoma
Tumour excision
What is the main complication of Phaeochromocytoma
HTN crisis (180/120) -Give Phentdiamine
What is given to treat HTN crisis
Phentadiamine (Alpha blocker)
