Hormones Flashcards

1
Q

What hormones are released by the anterior pituitary

A
FSH and LH
ACTH
GH
TSH
Prolactin
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2
Q

What is the precursor of FSH and LH and what secretes it

A

GnRH

Secreted by the gonads

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3
Q

What is the precursor of ACTH and its secretion

A

CRH

Secreted as cortisol from Adrenal gland

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4
Q

What is the precursor of GH (Somatotropin)

A

GHRH

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5
Q

What is the precursor of TSH and its secretion

A

TRH

Secreted by the thyroid as T3 and T4

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6
Q

What is the precursor of Prolactin

A

Dopamine

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7
Q

What is the function of FSH and LH

A

Germ cell development and hormone secretion

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8
Q

What is the function of ACTH

A

To release cortisol

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9
Q

What is the function of GH/Somatotropin

A

Stimulate IGF-1 production

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10
Q

What is the function of TSH

A

Release T3 and T4

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11
Q

What is the function of Prolactin

A

Milk production and bread development

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12
Q

What are the main complications of pituitary adenomas

A

Press on structures such as optic chasm
Hypopituitism
Hyperpituitism

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13
Q

What is the main function of insulin

A

Increase peripheral uptake of glucose

Glucose to glycogen

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14
Q

What is the mechanism of Insulin and how is it initiated

A

Glucose binds to GLUT2 receptor of pancreatic B cells = Insulin release
Insulin binds to Peripheral receptors = Activate tyrosine Kinase
GLUT4 channel increase expression = increased peripheral uptake

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15
Q

What two receptors are essential for insulin and glucose uptake

A

GLUT2 - Glucose binding

GLUT4 - Peripheral uptake

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16
Q

When should patients be treated with IM Glucagon

A

Unresponsive Hypoglycemia

17
Q

What two molecules bind with Thyroglobulin to produce steroids

A

T3 and T4

18
Q

What two hormones are secreted by the Posterior Pituitary

A

Oxytocin by Paraventricular

Vasopressin by suprorbital

19
Q

What is the function of Oxytocin

A

Induce labour and eject milk

20
Q

What is the function of Vasopressin

A

Reacts to low BP and stress

  • Vasoconstriction
  • Increase Aldosterone
  • Increase APO 2
21
Q

What are the main functions of cortisol

A
Increase protein/carb breakdown
Increase BP
Suppress immune system
Increase Osteoclast activity
increase insulin resistance
22
Q

What are the 4 layers of the adrenal gland

A

Zona Glomerulosa
Zona Fasciculata
Zona Reticularis
Adrenal Medulla

23
Q

Where is Aldosterone secreted from

A

Zona Glomerulosa

24
Q

Where is Cortisol secreted from

A

Zonal Fasciculata

25
Q

Where is Andogen/Sex hormones secretd from

A

Zona reticularis

26
Q

Where is NAd and Add secreted from

A

Adrenal Medulla