Hypothyroidism Flashcards

1
Q

What is the most common type of Hypothyroiditis in Developed World

A

Hashimoto’s

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2
Q

What Antibodies associate with Hashimoto’s

A

Anti-TPO !!!!!!
Anti- Thyroglobulin
Anti-TSH (uncommon)

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3
Q

What are the auto-immune causes of Hypothyroidism

A

Hashimoto

Atrophic thyroiditis

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4
Q

What are the iatrogenic causes of hypothyroidism

A

Surgery
Radiation
Radioablation

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5
Q

What are the congenital causes of Hypothyroidism

A
Thyroid ablasia
Pendred Syndrome(Thyroxine defect)
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6
Q

What are the iodine related causes of hypothyroidism

A

Infiltration

  • Sarcoidosis
  • Haemochromotosis
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7
Q

What are the peripheral features of hypothyroidism

A

Dry thick skin
Brittle hair
Loss of lateral third eyebrow

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8
Q

What are the head and neck features of Hypothyroidism

A

Macroglossia
Puffy face
Goitre

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9
Q

What are the cardiac features of Hypothyroidism

A

Bradycardia

Cardiomegaly

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10
Q

What are the neurological causes of Hypothyroidism

A

Carpal Tunnel syndrome
Slow reflex
peripheral neurpathy

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11
Q

What is the management of Hypothyroidism

A

1st = levothyroxine

Annual TSH check up

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12
Q

What is the changes in TSH, T3 and T4 between Primary and secondary causes of hypothyroidism

A

TSH-T3-T4
P= HIGH-LOW-LOW
S= ALL LOW
SC = HIGH - NORMAL -NORMAL

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13
Q

What are the investigations for Hypothyroidism

A
1st = Thyroid function test
Bloods = Anti TPO/Anti-Thyroglobulin w/Anaemia
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14
Q

What is the most common cause of Hypothyroidism in developing world

A

Iodine defficiency

Postpartum Thyroiditis

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15
Q

What is Postpartum thyroiditis

A

Like HASHIMOTO BUT…..

  • Acute after pregnancy
  • Resolves alone
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16
Q

Why should Levothyroxine dose be monitored carefully

A

Can cause hyperthyroidism

17
Q

What is the main complication of Hypothyroidim

A

Myxoedema Coma
-Rapid T4 Decrease
Hypothermia
Heart fail

18
Q

How is Myxoedema coma treated

A

Levothyroxine w/Abx and Hydrocortisone