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Pharmacy > PA 1 > Flashcards

PA 1 Flashcards

1
Q

What is in the sample?

A

Qualitative

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2
Q

How much is present in the sample?

A

Quantitative

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3
Q

Sum of all factors which contribute
directly or indirectly to the safety,
effectiveness, and reliability of the
product

A

Quality

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4
Q

Ensures that drug products are
designed and produced to meet or
exceed customer requirements for
effect and safety

A

Quality

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5
Q

Types of analysis

A

Based on sample size
Based on extent of determination
Based on nature of methods

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6
Q

Total amount of a CLASS or GROUP of active constituents

A

Proximate

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7
Q

Amount of a SINGLE CHEMICAL SPECIES in a sample

A

Ultimate

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8
Q

A book of public pharmacopeial
standards

A

USP/NF

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9
Q

generic or non- proprietary name of the
drug

A

Official title

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10
Q

a formula which shows the arrangement of the elements

A

Structural formula

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11
Q

the simplest formula

A

Empirical formula

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12
Q

overall weight of the compound

A

Molecular weight

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13
Q

Code numbers assigned by CAS to the chemical substance

A

Chemical Abstracts Service Number

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14
Q

Include names based on other systems of
nomenclature or naming like IUPAC

A

Other chemical names

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15
Q

A statement of purity and composition of the compound or drug which has been predetermined by the Pharmacopeia to be the purity

A

Official definition

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16
Q

the degree to which information
matches true or accepted values

A

Accuracy

17
Q

degree to which measurements
fluctuates around a central measurement

A

Precision

18
Q

manifest themselves by slight variations in a series of observations
made by the observer under identical conditions

A

Indeterminate errors

19
Q

Possible to partially determine their
value and reduce their effect on the
final result

A

Determinate errors

20
Q

a method of analysis
that determines the precise endpoint
of a reaction and therefore the
precise quantity of reactant in the
titration flask

A

Titration

21
Q

Volumetric or standard solution of known concentration

A

Titrant

22
Q

the active constituent to be analyzed

A

Analyte

23
Q

Chemicals capable of changing at or near the endpoint

A

Indicators

24
Q

Point when added titrant is chemically equivalent to the analyte in the sample

A

Equivalence point

25
Q

Experimental approximate of the
equivalence point

A

Endpoint

26
Q

the mathematical formula employed
in the calculation to find the quantity
of the constituent being analyzed

A

Stoichiometry

27
Q

grams of substance that is chemically equivalent to 1 mL of a volumetric solution

A

Titer

28
Q

a solution whose accurate concentration is known

A

Standard solution

29
Q

another standard solution of known concentration

A

Secondary solution

30
Q

a carefully weighed sample of a
substance of known concentration

A

Primary solution

31
Q

the number of equivalents of solute per liter of solution

A

Normality

32
Q

the number of moles of solute per liter of
solution

A

Molarity

33
Q

the number of moles of solute per 1000 g of
solvent

A

Molality

34
Q

process of establishing the accurate
concentration of a solution by allowing it
to react with a pure substance known as
primary standard

A

Standardization

35
Q

acidic titrant with basic analyte

A

Acidimetry

36
Q

basic titrant with acidic analyte

A

Alkalimetry

37
Q

conducted by introducing a standard acid/ base solution gradually from a buret into a solution of the base/ acid being assayed until chemically
equivalent amounts of each have reacted as shown by some change in properties of the mixture

A

Direct Titration

38
Q

carried out by dissolving the substance under
examination in an accurately measured quantity of standard solution known to be in excess and titrating the excess of the latter with another standard solution

A

Residual Titration

39
Q

developed by a Danish chemist named Johan Kjeldahl in 1883. This method was specifically developed for determining the
nitrogen contents in organic and inorganic substances

A

Kjeldahl method

Pharmacy (8 decks)

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