Oxidation Of FA Flashcards

1
Q

What is the site of b oxidation of fatty acids

A
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2
Q

What is the timing of b oxidation of FA

A

Fasting state

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3
Q

What are the 3 main phases of b oxidation of FA

A
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4
Q

Explain the activation of fatty acids

A
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5
Q

What is the importance of transport of long chin acylCoA (carnitine shuttle)

A
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6
Q

What are the components of transport of long chain AcylCoA (carnitine shuttle)

A
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7
Q

Explain the steps of carnitine shuttle

A
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8
Q

What is the aim of cycling reactions

A
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9
Q

Explain the steps of cycling reactions

A
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10
Q

What is the total amount of ATP from the cycling reactions

A

17 ATP

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11
Q

What is the function of malonyl CoA

A

Allosteric inhibitor of CAT1

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12
Q

What is the equations of the regulation step of b oxidation

A
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13
Q

What is the mechanism of regulation

A

Short term allosteric regulation (inhibition)

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14
Q

Explain the regulation in fasting and fed state

A
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15
Q

Why FA oxidation not active with FA synthesis at the same time?

A

Because when FA synthesis is active we have malonylCoA that stops FA oxidation.

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16
Q

What are the other types of FA oxidation

17
Q

Compare between b oxidation of odd number of FA and B oxidation of even number of FA

18
Q

Compare between b oxidation of unsaturated FA and B oxidation of saturated FA

A

Importance of both is energy production
In oxidation of saturated FA FADH2 is produced to form 2 ATP while in the oxidation of unsaturated FA this step is canceled, so less energy for the unsaturated FA

19
Q

Compare between omega oxidation and b oxidation

20
Q

Compare between alpha oxidation and b oxidation

21
Q

Compare between peroxisomal oxidation and b oxidation