Krebs Cycle Flashcards

1
Q

What is the Citric Acid Cycle also known as?

A

Krebs Cycle or Tricarboxylic Acid (TCA) Cycle

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2
Q

What percentage of ATP is synthesized via the Krebs Cycle?

A

Approximately 65-70%

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3
Q

What does the Krebs Cycle oxidize Acetyl-CoA to?

A

CO2 and H2O

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4
Q

Who proposed the Krebs Cycle and in what year?

A

Hans Adolf Krebs in 1937

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5
Q

What type of metabolic process is the Krebs Cycle primarily considered?

A

Catabolic

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6
Q

Where does the Krebs Cycle occur?

A

In the mitochondria

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7
Q

What are the substrates used in the Krebs Cycle?

A

Carbohydrates, fatty acids, and amino acids

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8
Q

Is the Krebs Cycle an aerobic or anaerobic process?

A

Aerobic process

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9
Q

What is the net energy yield from one glucose molecule in the Krebs Cycle?

A

38 ATP molecules

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10
Q

What is the first step of the Krebs Cycle?

A

Acetyl-CoA combines with oxaloacetate to form citrate

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11
Q

What high-energy molecules are produced in the Krebs Cycle?

A

NADH and FADH2

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12
Q

What regulates the Krebs Cycle?

A

Substrate availability, product inhibition, allosteric regulation

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13
Q

What is the role of Pyruvate Dehydrogenase (PDH) in the Krebs Cycle?

A

Converts pyruvate to Acetyl-CoA

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14
Q

True or False: The Krebs Cycle is a closed system.

A

False

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15
Q

Fill in the blank: The Krebs Cycle is the final common pathway for the oxidation of _______.

A

carbohydrates, fatty acids, and amino acids

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