Krebs Cycle Flashcards
What is the Citric Acid Cycle also known as?
Krebs Cycle or Tricarboxylic Acid (TCA) Cycle
What percentage of ATP is synthesized via the Krebs Cycle?
Approximately 65-70%
What does the Krebs Cycle oxidize Acetyl-CoA to?
CO2 and H2O
Who proposed the Krebs Cycle and in what year?
Hans Adolf Krebs in 1937
What type of metabolic process is the Krebs Cycle primarily considered?
Catabolic
Where does the Krebs Cycle occur?
In the mitochondria
What are the substrates used in the Krebs Cycle?
Carbohydrates, fatty acids, and amino acids
Is the Krebs Cycle an aerobic or anaerobic process?
Aerobic process
What is the net energy yield from one glucose molecule in the Krebs Cycle?
38 ATP molecules
What is the first step of the Krebs Cycle?
Acetyl-CoA combines with oxaloacetate to form citrate
What high-energy molecules are produced in the Krebs Cycle?
NADH and FADH2
What regulates the Krebs Cycle?
Substrate availability, product inhibition, allosteric regulation
What is the role of Pyruvate Dehydrogenase (PDH) in the Krebs Cycle?
Converts pyruvate to Acetyl-CoA
True or False: The Krebs Cycle is a closed system.
False
Fill in the blank: The Krebs Cycle is the final common pathway for the oxidation of _______.
carbohydrates, fatty acids, and amino acids