Ovarian Cancer Flashcards
1
Q
What genetic risks are there for ovarian cancer?
A
-Homologous recombination deficiency
-BRCA1/2 mutations
-HNPCC
2
Q
What is the adjuvant chemotherapy regimen?
A
paclitaxel, carboplatin
3
Q
What is the calvert equation?
A
AUC x (GFR +25)
-GFR = cockroft-gualt equation
-for carboplatin dosing
0.85 (140-age) x (kg)/ Scr x 72
4
Q
What is a type 1 hypersensitivity?
A
immediate reaction
-sx of anaphylaxis, itching, rash, chest tightness
5
Q
What is a type IV hypersensitivity?
A
delayed reaction
-erythema, induration
-T-Cell mediated
6
Q
What needs to happen if a patient develops a hypersensitivity reaction?
A
-patient needs to be desensitized
