Other GPR

Question 1

Corynebacterium diphtheriae

Answer 1

Chinese letters appearance. Exotoxin: encoded by beta-prophage. ADP-ribosylator of EF-2

“Pseudomembranous pharangitis: greyish-white membrane, with lymphadenopathy, myocarditis, & arrhythmias. Toxoid Vaccine prevents disease (DTP), not infection.
Lab diag. GPR with metachromatic (blue & red granules) & elek’s test for toxin. Black colonies on cystine-tellurite agar.
Coryne = club-shaped
ABCDEFG: (ADP ribosylation, Beta-prophage, Cornybacterium, Diptheria, EF-2, Granules).”

Question 2

Listeria monocytogenes

Answer 2

“Faculative Intracellular multiplication. Tumbling motility at 20-25C. Actin filaments - intracellular.
Toxins: Internalin, listeriolysin-O, Actin rockets.”

“Ingestion of unpasturized milk/cheese & deli meats.
Vaginal transmission during birth.
Amnionitis. Septicemia. Spontaneous abortion. Granulomatosis infantiseptica. Neonatal meningitis, meningitis in immuno-suppressed patients, in patients with liver disease. Mild gastroenteritis in healthy individuals.”