Other Bacteria Flashcards
Undulating fever
Brucella abortus
Infection from rabbits, deer or rodents; transmitted by tick bite (dermacentor)
Tularemia (Francisella tularensis)
Most virulent bacteria; causes buboes and cutaneous hemorrhage
Yersinia pestis (plague)
Animal bite infection
Pasturella multocida
Buttery colonies of pasturella multocida with musty odor due to production of _________
Indole
Reproductive tract infection in cattle, infection through contaminated dairy or direct contact with cows
Brucella abortus
Uses heat to stabilize carbolfuscin
Ziehl-Neelsen
Uses detergent to stabilize carbolfuscin
Kinyoun
Lipids of mycobacterium tuberculosis (2)
- Mycolic acid, 2. Wax D
Prevents phagolysosome fusion in M. tuberculosis
Exported repetitive protein (sulfatides)
Prevents leukocyte migration in TB
Cord factor
Delayed hypersensitivity against TB; basis for the PPD test
Tuberculin surface protein
Subpleural TB granuloma
Ghon’s focus
Ghon’s focus + lymph node
Ghon’s complex
Radiologically detectable TB calcification
Ranke’s complex
Reactivation TB, usually in the apices
Simon’s focus
TB may be secondarily infected with ____________
Aspergillus fumigatus
PPD cutoff value: Philippines
> 8mm
PPD cutoff value: immunosuppressed
> 5mm
PPD cutoff value: high risk population
> 10 mm
PPD cutoff value: low risk population
> 15 mm
Most common extrapulmonary TB
Scrofula
Other use of BCG vaccine other than TB prevention
Intravesical injection for urinary bladder CA
Pulmonary disease when CD4
Mycobacterium avium intracellulare complex
Must be cultured on the footpads of a mouse or armadillo
Mycobacterium leprae
Macrophages filled with M. leprae
Globi
Free bacilli, not contained in globi
Red Snappers
Marked tissue destruction, many lesions, many acid-fast bacilli, high infectivity, negative lepromin skin test due to reduced or absent cell mediated response
Lepromatous leprosy
Minimal tissue destruction, few lesions, few acid-fast bacilli, low infectivity, positive lepromin skin test due to intact cell mediated response
Tuberculoid leprosy
Hypopigmented plaques, thickened superficial nerves and significant anesthesia
Tuberculoid leprosy
Leonine facies, erythema nodosum leprosum
Lepromatous leprosy
- Tx for lepromatous leprosy
2. Side effects of the drugs
- Dapsone (methemoglobinemia), 2. Rifampicin (hepatotoxic, orange colored secretions), 3. Clofazimine (bronze discoloration)