Gram Positive Cocci Flashcards
Catalase positive, coagulase positive
Staph aureus
Catalase positive, coagulase negative, novobiocin sensitive
Staph epidermidis
Catalase positive, coagulase negative, novobiocin resistant
Staph saprophyticus
Halotolerant on mannitol salt agar
Staph aureus
Pigment responsible for gold color of Staph aureus
Staphyloxanthin
Virulence factor of Staph aureus that destroys neutrophils and macrophages
Panton-Valentine (PV) Leukocidin
Tissue penetrance virulence factors
Hyaluronidase, collagenase, lipase, fibrinolysin
Causes epidermal separation in SSSS by cleaving desmoglein in desmosomes
Exfoliatin
Causes Staph aureus toxic shock syndrome
TSST-1
Characteristics of Staph aureus endocarditis (3)
- Most common cause of acute endocarditis; 2. Tricuspid valve; 3. IV drug users
Sequestered osteomyelitis in the metaphysis of long bones
Brodie abscess
Level of epidermal separation in SSSS
stratum granulosum
Level of epidermal separation in SJS/TEN
Dermoepidermal junction
Strawberry tongue, desquamating rash, multiorgan involvement; no site of pyogenic inflammation, culture negative
Staph Toxic shock syndrome
Side effect of vancomycin if given as a bolus
Red Man syndrome
Treatment options for staph aureus (3)
- Oxacillin, nafcillin, dicloxacillin; 2. Vancomycin if MRSA; 3. Linezolid if vancomycin-resistant
Criteria for food poisoning (2)
- At least 2 people with the same symptoms; 2. Causative organism has been identified
Possesses a glycocalyx; forms a biofilm that adheres most especially to prostheses
Staph epidermidis
2nd most common cause of UTI in sexually active women
Staph saprophyticus
Treatment for staph saprophyticus
TMP-SMX, quinolones