Other AP Flashcards

1
Q

Dx of: lymphocytic bronchiolitis, mild interstitial lymphocytic inflammation, and poorly-formed granulomas

A

Hypersensitivity pneumonitis (Extrinsic allergic alveolitis)

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2
Q

3 findings in Hypersensitivity pneumonitis

A

lymphocytic bronchiolitis
mild interstitial lymphocytic inflammation
poorly-formed granulomas

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2
Q

1p, 19q

A

Co-deletion in oligodendroglioma

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3
Q

Most common genetic aberration in meningioma

A

Ch 22

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4
Q

Isochromosome 17q

A

Most common genetic abnormality in medulloblastoma

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5
Q

Genetic alteration in medulloblastoma with poor prognosis

A

Myc amplification

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6
Q

Intraventricular brain tumors

A
SEGA
Ependymoma
Subependymoma
Choroid plexus tumors
Pineal tumors
Colloid cyst
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7
Q

Cystic tumor with mural nodule

A
Pilocytic astrocytoma
PXA
Ganglion cell tumor
Hemangioblastoma
Craniopharyngioma
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8
Q

Most common H&N location for lobular capillary hemangioma

A

Anterior nasal septum (Kisselbach’s triangle)

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9
Q

Causative agent of rhinoscleroma

A

Klebsiella rhinoscleromatis

Organisms seen in Mikulicz cells (clear histiocytes)

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10
Q

Causative agent of rhinosporidiosis

A

Rhinosporidium seeberi

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11
Q

Triad of histo findings in Wegeners

A

Geographic necrosis
Granulomatous inflamm
Vasculitis

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12
Q

Histology findings in cylindrical cell papilloma (oncocytic schneiderian papilloma)

A
2 cell layers
Cilia
Intraepithelial mucin cysts
Goblet cells
Neutrophils
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13
Q

Most common sarcoma of H&N

A

Rhabdomyosarcoma

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14
Q

Nasopharyngeal carcinoma assd with…

A

EBV

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15
Q

Looks like colon carcinoma in nose

A

High-grade sinonasal adenocarcinoma

May have mucinous or signet ring cell types

16
Q

Assd with occupational exposures to wood dust and leather processing

A

High-grade (intestinal type) sinonasal adenocarcinoma

17
Q

Ddx with malignant granular cell tumor

A

Paraganglioma

Alveolar soft part sarcoma

18
Q

Prognosis of spindle cell carcinoma of larynx

A

Generally poor, but do not tend to invade deeply due to polyploid growth pattern

19
Q

Chronic otitis media with glandular inclusions

A

It exists

20
Q

Itchy periaural papules that bleed

A

Angiolymphoid hyperplasia with eosinophilia
Histo similar to Kimura dz
Assd lymphadenopathy and peripheral eosinophilia

21
Q

Benign ear tumor that may look like carcinoid

A

Middle ear adenoma

23
Q

Papillary neoplasm of endolymphatic sac origin (Heffner tumor)

A

Assd with VHL

Arises in temporal bone

24
Q

Most common cause of allergic fungal sinusitis

A

dematiaceous fungi

25
Q

Location of inverted papilloma

A

lateral nasal wall

26
Q

Respiratory epithelial adenomatoid hamartoma

A

(REAH) ddx of inverted papilloma
periglandular hyalinization
thin respiratory epithelium

27
Q

Stains positive in glomangiopericytoma

A

SMA, Factor XIIIA

28
Q

Staining in olfactory neuroblastoma

A

s100 in sustentacular pattern

29
Q

Staining in sinonasal undifferentiated carcinoma

A

cytokeratin only

30
Q

ddx of sinonasal undifferentiated carcinoma

A
sinonasal neuroendocrine carcinoma
lymphoepithelial carcinoma
Ewing/PNET
Melanoma
Rhabdomyosarcoma
31
Q

Rhomboid crystals on EM

A

alveolar soft part sarcoma

32
Q

“corncob” on EM

A

melanosome (melanoma, clear cell sarcoma)