Other AP Flashcards
Dx of: lymphocytic bronchiolitis, mild interstitial lymphocytic inflammation, and poorly-formed granulomas
Hypersensitivity pneumonitis (Extrinsic allergic alveolitis)
3 findings in Hypersensitivity pneumonitis
lymphocytic bronchiolitis
mild interstitial lymphocytic inflammation
poorly-formed granulomas
1p, 19q
Co-deletion in oligodendroglioma
Most common genetic aberration in meningioma
Ch 22
Isochromosome 17q
Most common genetic abnormality in medulloblastoma
Genetic alteration in medulloblastoma with poor prognosis
Myc amplification
Intraventricular brain tumors
SEGA Ependymoma Subependymoma Choroid plexus tumors Pineal tumors Colloid cyst
Cystic tumor with mural nodule
Pilocytic astrocytoma PXA Ganglion cell tumor Hemangioblastoma Craniopharyngioma
Most common H&N location for lobular capillary hemangioma
Anterior nasal septum (Kisselbach’s triangle)
Causative agent of rhinoscleroma
Klebsiella rhinoscleromatis
Organisms seen in Mikulicz cells (clear histiocytes)
Causative agent of rhinosporidiosis
Rhinosporidium seeberi
Triad of histo findings in Wegeners
Geographic necrosis
Granulomatous inflamm
Vasculitis
Histology findings in cylindrical cell papilloma (oncocytic schneiderian papilloma)
2 cell layers Cilia Intraepithelial mucin cysts Goblet cells Neutrophils
Most common sarcoma of H&N
Rhabdomyosarcoma
Nasopharyngeal carcinoma assd with…
EBV
Looks like colon carcinoma in nose
High-grade sinonasal adenocarcinoma
May have mucinous or signet ring cell types
Assd with occupational exposures to wood dust and leather processing
High-grade (intestinal type) sinonasal adenocarcinoma
Ddx with malignant granular cell tumor
Paraganglioma
Alveolar soft part sarcoma
Prognosis of spindle cell carcinoma of larynx
Generally poor, but do not tend to invade deeply due to polyploid growth pattern
Chronic otitis media with glandular inclusions
It exists
Itchy periaural papules that bleed
Angiolymphoid hyperplasia with eosinophilia
Histo similar to Kimura dz
Assd lymphadenopathy and peripheral eosinophilia
Benign ear tumor that may look like carcinoid
Middle ear adenoma
Papillary neoplasm of endolymphatic sac origin (Heffner tumor)
Assd with VHL
Arises in temporal bone
Most common cause of allergic fungal sinusitis
dematiaceous fungi
Location of inverted papilloma
lateral nasal wall
Respiratory epithelial adenomatoid hamartoma
(REAH) ddx of inverted papilloma
periglandular hyalinization
thin respiratory epithelium
Stains positive in glomangiopericytoma
SMA, Factor XIIIA
Staining in olfactory neuroblastoma
s100 in sustentacular pattern
Staining in sinonasal undifferentiated carcinoma
cytokeratin only
ddx of sinonasal undifferentiated carcinoma
sinonasal neuroendocrine carcinoma lymphoepithelial carcinoma Ewing/PNET Melanoma Rhabdomyosarcoma
Rhomboid crystals on EM
alveolar soft part sarcoma
“corncob” on EM
melanosome (melanoma, clear cell sarcoma)