GI Path Flashcards
Sign that MALT lymphoma is less likely to respond to abx
t(11;18)
Type of gastritis with, pernicious anemia, increased serum gastrin and assd carcinoids
Gastritis Type A
H.Pylori assd gastritis
Gastritis Type B
Infections assd with Menetrier dz
H. pylori and CMV
Risk of dysplasia in FAP assd fundic gland polyps
up to 40%
Mutations assd with sporadic fundic gland polyps
Beta-catenin
Peutz-Jeghers associations
STK gene, ch19 Pancreatic tumors Adenoma malignum cervix SCTAT Sclerosing Sertoli cell tumor Breast CA
Benign lesion on the differential with GIST
Inflammatory fibroid polyp (inflammation and eosinophils
Type 2 gastric carcinoids are assd with…
MEN 1 and 2
Type 1 gastric carcinoids are assd with…
Type A gastritis
Giardia prevalence
5%
Follow-up method after tx for Whipple dz
PCR (PAS-D may still be +)
Histology of strongyloides hyperinfection
Eos and crystals aorund filarial larvae, Splendore-Hoeppli
Most sensitive and specific test for celiac
anti-tissue transglutaminase
HLA types assd with celiac
DQ2 and DQ8
Type of T-cells in epithelium of celiac
Gamma-delta
What signals an increased risk of enteropathy assd T cell lymphoma in celiac
Loss of CD8 positivity
GI histology of Waldenstrom
IgM deposition in small bowel lacteals
GI histology of Abetalipoproteinemia
lipid globules in enterocytes of small bowel
Aggressive carcinoid generally found in the appendix
goblet cell carcinoid (adenocarcinoid)
Psammomatous somatistatinoma
only occurs at Ampulla of Vater
Assd with NF1
“flask-shaped” ulcer in colon
amebiasis (may also see erythrophagocytosis)
Spirochetosis histology
very thick layer on apex of mucosa
Type of collagen in normal colon basement membrane and in collagenous colitis
Normal = Collagen IV
Collagenous colitis = Collagens I, III, VI, tenascin
