More AP

Question 1

Necrotizing sialometaplasia

Answer 1

mimics CA
Squamous metaplasia of ducts
lobular configuration

Question 2

IHC of clear cell hyalinizing carcinoma

Answer 2

CEA+, P63+

Question 3

IHC and nuclear features of polymorphous low grade carcinoma

Answer 3

S100+, open, vesicular nuclei

Question 4

IHC for salivary duct CA

Answer 4

Androgen receptor+ Her2+

Question 5

Painful salivary gland tumors

Answer 5

Adenoid cystic CA

Acinic cell CA

Question 6

Infection assd with pulmonary malakoplakia

Answer 6

Rhodococcus equi

Question 7

Pulmonary disorders with lymphangitic pattern

Answer 7

sarcoid
lymphoma
kaposi
langerhans

Question 8

Pulmonary capillary hemangiomatosis

Answer 8

causes pulm htn

presents with hemoptysis

Question 9

Dirofilariasis in the lung

Answer 9

Dead worms embolize from the heart to cause nodular infarcts with eosinophils

Question 10

Diffuse panbronchiolitis

Answer 10

Interstitial foamy macrophages
Bronchiolocentric acute and chronic inflammation
Japanese

Question 11

Alveolar adenoma

Answer 11

Multicystic proliferations

Cysts with epithelial lining and mesenchymal cell prolif

Question 12

Congenital lobar emphysema

Answer 12

infants

caused by partial obstruction of bronchus

Question 13

Placental transmogrification

Answer 13

lung parenchyma that looks like chorionic villi

seen in Giant Bullous Emphysema

Question 14

Most common mesenchymal tumor os the liver in children

Answer 14

infantile hemangioendothelioma

Question 15

“hypermature” chorionic villi assd with

Answer 15

uteroplacental insufficiency (ex. pre-eclampsis)

Question 16

Liver features in pts with AP polycystic kidney dz

Answer 16

fibrosis around portal tracts

dilation of bile ducts (ductal plate malformation

Question 17

Salivary gland tumor with defining translocation

Answer 17

Mammary analog secretory CA

t(12;15) ETV6-NTRK3

Question 18

Variant of PTC with squamous metaplasia

Answer 18

Diffuse sclerosing PTC

Question 19

Variant of PTC assd with FAP

Answer 19

Cribriform morular variant

beta-catenin +

Question 20

Genetic alteration seen in PTC assd with radiation

Answer 20

RET/PTC translocation

Question 21

Most common genetic alteration in PTC

Answer 21

BRAF 7q23

Question 22

Genetics of follicular lesiosn

Answer 22

PAX8/PPAR-gamma

Question 23

Primary brain tumor that can metastasize to liver and lungs

Answer 23

gliosarcoma

Question 24

Tumor other than meningioma with “dura tail sign”

Answer 24

Desmoplastic infantile astrocytoma/gangliocytoma

Question 25

Two syndromes assd with medulloblastoma

Answer 25

Gorlin (Sonic-Hedgehog pathway)

Turcot (APC gene, WNT pathway)

Question 26

Desmoplastic medulloblastoma mutation

Answer 26

patched gene, sonic-hedgehog pathway