OTC Flashcards
Difference btw OTC and prescription drugs?
Patient gets OTC after self assessment and both regulated by FDA
What things need to be on OTC labels?
Product name, Active ingredients, Purpose, Uses, Warnings, Directions, Other information, Inactive ingredients
Most sedating 1st OTC drug? Product Name
Diphenhydramine - Benadryl
Most common 2nd generation- non sedating
Cetirizine - Zyrtec
Preferred Long Acting Decongestant
Oxymetazoline and xylometazoline
Methamphetamine precursor
Pseudoephedrine
Acetaminophen toxicity and interactions and cautions
Hepatotoxic interactions with CYP inducers.
Alcohol and Cirrhosis
NSAIDS toxicity, interactions and cautions
Renal failure, interact with warfarin, decrease antihypertensive effect and caution with gout, aspirin induced asthma
Number 1 cause of acute hepatic failure is
Hepatotoxicity
Ist generation antihistamine effect against what?
E.g of 1st gen antihistamines?
Motion sickness with H1 inhibition in the CNS
Diphenhydramine, dimenhydrinate
4 Components of Coricidin
Chlorpheniramine( 1st gen antihistamine) Pseudoephedrine ( vasoconstirction), Acetaminophen and Dextromethorphan( cough)
If one has HBP, what component of Coricidin is taken off?
Pseudoephedrine
Anticholiinergic interactions. What drug?
Oxybutynin
Pseudoephedrine interactions
alpha agonist so vasoconstriciton
Topical decongestants interactions
rebound congestion/ rhinitis medicamentosa
Dextromethorphan metabolism. Overdose
Cough med metabolized by CYP2D6. Overdose causes phecyclidine effect (addictive). So co-formulated with guaifenesin to cause N/V, diarrhea if taken in high amounts
Cough and cold age minimum?
6 years old. Honey helps but fear of botulism
Drugs that can affect BP
Ephedrine, Epinephrine, Ibuprofen, Phenylephrine, Pseudoephedrine, theophylline
The main target OTC cough ingredient
Dextromethorphan
Easily producing a “high”
Solvents, Fuels, Anesthetics, Volatile alkyl nitrates
Nitrites antidote
Methylene blue
Death by inhalants is by
Cardiac arrhythmias, aspirated vomit
Energy drinks “Foods or Direct Supplement” main ingredient
Caffeine
Antacids ADE
kidney stones
Bismuth subsalicylate ADE ( antidiarrheal)
Anticoagulation
Constipation medications
Chelation and electrolyte imbalance
Ist drug of choice for pain n children
Acetaminophen due to Reyes syndrome
OTC prescription pharmacists can prescribe in future
Diabetes, asthma, migraines, HTN, drug overdose