Geriatrics Flashcards
Widely used phenotype for frailty
> 3 of the following criteria. Weight loss, exhaustion, weak grip strength, slow walking speed and low physical activity
Serum creatinine not used to measure kidney function in elders why?
Less muscle mass so less creatinine in circulation
Function of Cockcroft-Gault
Calculate creatinine clearance
Possibilities of anticholinergic effects
addiction, abuse, respiratory depression and confusion
Elderly use of Benzodiazepines
Anxiety use and one should use short acting
Examples of Benzodiazepines to use with elders
Alprazolam, Temazepam, and Lorazepam
Withdrawal symptoms of Benzodiazepines
Rebound Insomnia and falls
Strong anticholinergic and sedative Antidepressant to avoid in elderly ( TCA)
Amitriptyline
SSRIs better than TCA for elderly because
Low cardiotoxicity, orthostatic hypotension and anticholinergic. E.g are Citalopram, Escitalopram
What antiarrhythmic drug is contraindicated with the elderly and why?
Disopyrmide - anticholinergic properties, glaucoma, urine retention, increased HR, heart block and heart failure( potentially inappropriate medication)
Hypoglycemia effect on elderly
Insulin
GI and intracranial bleeding in elderly
Warfarin
Heart Block, impaired cognition
Digoxin
33% of ED ADE in elderly due to
insulin, digoxin and warfarin
Goals of Care of elderly drugs
Centralization and reappraisal of need to use some drugs and its duration