Osteoporosis

Question 1

OP most common in

Answer 1

Women

Question 2

Morbidity and mortality in men and women

Answer 2

Men: 30%

Women 9%

Question 3

Collagen is ___ and provides

Answer 3

Protein

Soft framework

Question 4

Calcium phosphate is ___

What does it do?>

Answer 4

Mineral

Add strength and harden framwork

Question 5

Cortical bone characteristics

Answer 5

Outer shell
Shaft
80% of skeletal mass

Question 6

Cancellous/spongy trabecular bone characteristics

Answer 6

Inner part of bone, end of long bone

20% mass

Question 7

Process of bone remodeling is

Answer 7

Resorbtion and formation of bone

Question 8

Cells that break bone down

Whats lifespan?

Answer 8

Osteoclasts

3 weeks

Question 9

Cells that form new bone and life span

Answer 9

Osteroblasts

3 months

Question 10

What responds to mechanical strain by sending signals to osteoblasts to increase bone formation or osteoclasts to remove?

Answer 10

Osteocytes

Question 11

How does osteoporosis occur?

Answer 11

Mismatch b/w osteoblasts/clasts

Question 12

What are other factors of osteoporosis

Answer 12

Change in hormone postmenopause

Low calcium and vitamin D

Question 13

Largest amount of bone tissue person has in their life

Answer 13

Peak bone mass

Question 14

Peak bone mass attained @ what ages?

Answer 14

18 girls

19/20 guys

Question 15

Growth spur occurs at what ages and how much of total bone mass is accumulated in this period?

Answer 15

11-14 for girls
13-17 for guys

40%

Question 16

What are the 3 types of Osteoporosis?

Answer 16

Generalized
Regional
Localized

Question 17

OP that involves the whole skeleton

Answer 17

Generalized OP

Question 18

OP of limb or region of skeleton

Answer 18

Regional OP

Question 19

OP involving focal areas of bone

Answer 19

Localized OP

Question 20

Bone loss associated with biological changes that occur during life span

Answer 20

Primary OP

Question 21

2 types of primary OP and association

Answer 21

Type 1: post menopause decreased estrogen

Type 2: aging process

Question 22

OP that occurs at any age

Answer 22

Secondary OP

Question 23

Bone loss in secondary OP characterized by

Answer 23

Med. conditions
Malnourished
Meds
Immob

Question 24

“ACCESS leads to OP

Answer 24

Alcohol use
Corticosteroid
Calcium low
Estrogen low
Smoking
Sedentary life

Question 25

What does FRAX generate?

Answer 25

10 year probability of OP event

Question 26

What does FORE calculate

Answer 26

Estimate 10 year fracture risk for those not receiving treatment for OP

Question 27

Dexa focuses on what 2 areas

Answer 27

Hip and spine

Question 28

What is considered the best predictor of hip Fx>?

Answer 28

HIP BMD by DXA

Question 29

What T score established DX of OP

Question 30

Z score compares you to ___

What is a low score?

Answer 30

Population of same sex age ethnicity

Question 31

Purpose of BMD

Answer 31

Predict risk of future fracture
Determine use of meds
Presence of OP

Question 32

Can you determine BMD from xray?

Answer 32

Naw

Question 33

Most common OP Fx

Answer 33

Vertebral

Question 34

Severerity of Fx determined by

Answer 34

Measuring amt. of vertebral height reduction

Question 35

Red flags of OP

Answer 35

Height loss >1 inch
Previous Fx.
Fam history
Kyphosis

Question 36

Contraindications for OP

Answer 36

Flexion
ADL w/ rounded spine
Sidebend/twist