OSTEONECROSIS AND OSTEOCHONDROSIS Flashcards
Unit 3 study
Osteonecrosis: Defined as
death of the osseous cellular components and marrow of bone d/t inadequate blood supply
M/C hematologic condition of bone
Osteonecrosis
What is the AKA for Osteonecrosis
Ischemic necrosis,
aseptic necrosis,
avascular necrosis,
bone infarction
What is the first and second MC avascular necrosis site involved in osteonecrosis?
MC Femoral head
2nd MC Humeral head
Osteonecrosis bone infarct occurs where
Metaphseal or
Diaphyseal
What term is used when osteonecrosis is in the bone end or juxta-articular involvement?
What is the MC location?
Avascular necrosis
Femoral head, 2nd mc is humeral head
The term Bone infarct is used when osteonecrosis is in what part of the bone?
Metaphyseal or Diaphyseal
What is the latent period for symptoms to develop in osteonecrosis?
a few weeks to 1 year
Name the 4 mechanisms of infarction
Intraluminal obstruction
Arterial wall disease
Vascular compression
Physical disruption of vessel
A temporary loss of blood flow can lead to
bone ischemia
A prolonged decrease in blood flow can lead to
Bone infarction
What are the more common causes (predispose) of osteonecrosis?
Vascular, Drugs, Congenital, Trauma
Infection, Inflammatory, Autoimmune, Endocrine
Spontaneous
Osteonecrosis vascular cause is associated with
Hemoglobinopathies
What OSTEONECROSIS: cause is associated with Infections?
Septic emboli
What OSTEONECROSIS: cause is associated with Drugs/Toxins?
Alchololism and steroids
What OSTEONECROSIS: cause is associated with inflammation?
Pancreatitis