Histological Origin classification of bone tumors

Question 1

What malignant tumor has an osteogenic cell origin?

Answer 1

Osteosarcoma and paraosseous osteosarcoma

Question 2

What benign tumors are osteogenic cell origin?

Answer 2

osteoid osteoma, osteoblasto, and osteoma

Question 3

What malignancy of tumors has an origin in the notochord?

Answer 3

chordoma

Question 4

Mineralization of the matrix in osteogenic and cartilaginous tumors is known as

Answer 4

matrix ossification/calcification

Question 5

What type of mineralization produces a solid, cloud-like or ivory-like pattern of increased density on radiographs?

Answer 5

osteoid

Question 6

Cartilaginous matrix appears as what on radiograph?

Answer 6

stippled, flocculent, or ring and arc-like

Question 7

Longitudinal refers to what part of the bone?

Answer 7

epi-, meta-, and diaphyseal

Question 8

Axial refers to what location of a lesion within the bone?

Answer 8

central, eccentric, cortical, para-osseous/juxta-cortical, extra-osseous

Question 9

What primary malignancy cause for amputation as its primary treatment?

Answer 9

Osteosarcoma

Question 10

What conditions have a poor prognosis?

Answer 10

multiple myeloma, Ewing’s sarcoma and Osseous metastasis

Question 11

What does the “O” in IHOP represent for ivory vertebra?

Answer 11

Osteoblastic metastatic carcinoma

Question 12

Spiculated, arcs and rings, popcorn and flocculated are descriptions of what matrix mineralization or calcification?

Answer 12

chondroid

Question 13

What tumor can go away on its own (can heal on its own)?

Answer 13

Osteoid osteoma

Question 14

What condition has the periosteal response speculated (sunburst) and Codman’s triangle?

Answer 14

osteosarcoma

Note this condition deceases ROM.

Question 15

What condition leads to cannonball in the lungs?

Answer 15

Osteosarcoma or metastasis

Question 16

Cancer is least likely to metastasize to which part of the body?

Answer 16

Brain d/t blood brain barrier

Question 17

What is the cardinal first sign/symptom of multiple myeloma?

Answer 17

back pain

Question 18

Name the pathologic feature of multiple myeloma.

Answer 18

Amyloid build up

Question 19

Name the hallmark of Multiple Myeloma.

Answer 19

multiple punched out lesions

Question 20

Name the MC radiographic appearance of multiple myeloma

Answer 20

Generalized osteopenia

Question 21

Name the round cell lesions.

Answer 21

Ewing’s sarcoma and Multiple myeloma

Question 22

What is the classic sign seen in Hodgkin’s Lymphoma?

Answer 22

vertebral anterior scalloping

Question 23

Alkaline phosphatase is elevated in what conditions?

Answer 23

Paget’s Dz, Osteoblastic metastasis carcinoma and Hodgkin’s lymphoma

Question 24

Sauceration is a radiographic feature seen in what condition?

Answer 24

Ewing’s sarcoma

Question 25

What is the difference b/w osteosarcoma and Ewing’s?

Answer 25

osteosarcoma will decrease ROM and Ewing’s mimics an infection