Histological Origin classification of bone tumors Flashcards
What malignant tumor has an osteogenic cell origin?
Osteosarcoma and paraosseous osteosarcoma
What benign tumors are osteogenic cell origin?
osteoid osteoma, osteoblasto, and osteoma
What malignancy of tumors has an origin in the notochord?
chordoma
Mineralization of the matrix in osteogenic and cartilaginous tumors is known as
matrix ossification/calcification
What type of mineralization produces a solid, cloud-like or ivory-like pattern of increased density on radiographs?
osteoid
Cartilaginous matrix appears as what on radiograph?
stippled, flocculent, or ring and arc-like
Longitudinal refers to what part of the bone?
epi-, meta-, and diaphyseal
Axial refers to what location of a lesion within the bone?
central, eccentric, cortical, para-osseous/juxta-cortical, extra-osseous
What primary malignancy cause for amputation as its primary treatment?
Osteosarcoma
What conditions have a poor prognosis?
multiple myeloma, Ewing’s sarcoma and Osseous metastasis
What does the “O” in IHOP represent for ivory vertebra?
Osteoblastic metastatic carcinoma
Spiculated, arcs and rings, popcorn and flocculated are descriptions of what matrix mineralization or calcification?
chondroid
What tumor can go away on its own (can heal on its own)?
Osteoid osteoma
What condition has the periosteal response speculated (sunburst) and Codman’s triangle?
osteosarcoma
Note this condition deceases ROM.
What condition leads to cannonball in the lungs?
Osteosarcoma or metastasis
Cancer is least likely to metastasize to which part of the body?
Brain d/t blood brain barrier
What is the cardinal first sign/symptom of multiple myeloma?
back pain
Name the pathologic feature of multiple myeloma.
Amyloid build up
Name the hallmark of Multiple Myeloma.
multiple punched out lesions
Name the MC radiographic appearance of multiple myeloma
Generalized osteopenia
Name the round cell lesions.
Ewing’s sarcoma and Multiple myeloma
What is the classic sign seen in Hodgkin’s Lymphoma?
vertebral anterior scalloping
Alkaline phosphatase is elevated in what conditions?
Paget’s Dz, Osteoblastic metastasis carcinoma and Hodgkin’s lymphoma
Sauceration is a radiographic feature seen in what condition?
Ewing’s sarcoma
What is the difference b/w osteosarcoma and Ewing’s?
osteosarcoma will decrease ROM and Ewing’s mimics an infection
