Histological Origin classification of bone tumors Flashcards

1
Q

What malignant tumor has an osteogenic cell origin?

A

Osteosarcoma and paraosseous osteosarcoma

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2
Q

What benign tumors are osteogenic cell origin?

A

osteoid osteoma, osteoblasto, and osteoma

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3
Q

What malignancy of tumors has an origin in the notochord?

A

chordoma

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4
Q

Mineralization of the matrix in osteogenic and cartilaginous tumors is known as

A

matrix ossification/calcification

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5
Q

What type of mineralization produces a solid, cloud-like or ivory-like pattern of increased density on radiographs?

A

osteoid

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6
Q

Cartilaginous matrix appears as what on radiograph?

A

stippled, flocculent, or ring and arc-like

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7
Q

Longitudinal refers to what part of the bone?

A

epi-, meta-, and diaphyseal

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8
Q

Axial refers to what location of a lesion within the bone?

A

central, eccentric, cortical, para-osseous/juxta-cortical, extra-osseous

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9
Q

What primary malignancy cause for amputation as its primary treatment?

A

Osteosarcoma

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10
Q

What conditions have a poor prognosis?

A

multiple myeloma, Ewing’s sarcoma and Osseous metastasis

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11
Q

What does the “O” in IHOP represent for ivory vertebra?

A

Osteoblastic metastatic carcinoma

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12
Q

Spiculated, arcs and rings, popcorn and flocculated are descriptions of what matrix mineralization or calcification?

A

chondroid

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13
Q

What tumor can go away on its own (can heal on its own)?

A

Osteoid osteoma

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14
Q

What condition has the periosteal response speculated (sunburst) and Codman’s triangle?

A

osteosarcoma

Note this condition deceases ROM.

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15
Q

What condition leads to cannonball in the lungs?

A

Osteosarcoma or metastasis

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16
Q

Cancer is least likely to metastasize to which part of the body?

A

Brain d/t blood brain barrier

17
Q

What is the cardinal first sign/symptom of multiple myeloma?

A

back pain

18
Q

Name the pathologic feature of multiple myeloma.

A

Amyloid build up

19
Q

Name the hallmark of Multiple Myeloma.

A

multiple punched out lesions

20
Q

Name the MC radiographic appearance of multiple myeloma

A

Generalized osteopenia

21
Q

Name the round cell lesions.

A

Ewing’s sarcoma and Multiple myeloma

22
Q

What is the classic sign seen in Hodgkin’s Lymphoma?

A

vertebral anterior scalloping

23
Q

Alkaline phosphatase is elevated in what conditions?

A

Paget’s Dz, Osteoblastic metastasis carcinoma and Hodgkin’s lymphoma

24
Q

Sauceration is a radiographic feature seen in what condition?

A

Ewing’s sarcoma

25
Q

What is the difference b/w osteosarcoma and Ewing’s?

A

osteosarcoma will decrease ROM and Ewing’s mimics an infection