Osteoarthritis

Question 1

what is arthritis?

Answer 1

joint pain

Question 2

what is arthralgia?

Answer 2

sensation of pain

Question 3

which joints are affected by OA?

Answer 3

small joints of fingers, knees hip, spines

Question 4

what is Bouchard’s nodes?

Answer 4

they are bumps on proximal interphalanges joints

Question 5

what is heberden’s nodes

Answer 5

bumps on distal interphalanges joints

Question 6

what are osteophytes?

Answer 6

bone spurs

Question 7

what is subchondral sclerosis?

Answer 7

cartilage ulceration

Question 8

is OA inflammatory or non inflammatory?

Answer 8

non

Question 9

what is the recommended management for OA?

Answer 9

panadol+ NSAIDs
weight loss, physical therapy, support
joint replacement
no need PO steroids
can inject intra articular steroids or hyaluronic acid

Question 10

risk factors for OA:

Answer 10

age above 65, female, joint trauma, family hx, obesity

Question 11

does OA have morning stiffness? how long?

Answer 11

yes, less than 30 minutes

Question 12

what are the typical symptoms of RA?

Answer 12

advanced symmetrical involvement of the joints of hands ( proximal interphalangeal and metacarpophalangeal joints. ) cartilage loss+ bone erosion.

Question 13

what are the risk factors of RA?

Answer 13

HLA-DL4 gene
smoking

Question 14

pathophysiology of RA

Answer 14

gene: failure of tolerance and unregulated lymphocyte activation.

smoking: alter protein to form antigens that trigger immune system to produce autoantibodies. Rhematoid factor and anti CCP . this results in synoviocyte activation, cytokine production and inflammation. thus destruction of cartilage and bones

Question 15

what is felty syndrome?

Answer 15

neutropenia, splenomegaly

Question 16

what medications and supplements should you prescribe for OA?

Answer 16

panadol nsaids, opiods, intraarticular hyaluronic acid, glucocorticoids, chondroitin supplement, glucosamine