Ossification Flashcards
Osteogenesis/ ossification of bone
Bone tissue formation
Osteogenesis/ ossification of bone stages
Bone formation (2 month of development) Postnatal bone growth (until early adulthood) Bone remodeling and repair (life long)
Two types of ossification
Intramebraneous ossification
Endochondral ossification
Intramembraneous ossification
Membrane bone develops from fibrous membrane
Forms most flat bones
Intramembraneous ossification step one
Ossification center appear in fibrous connect tissue membrane
Intramembraneous ossification step two
Bone matrix (osteoid) is secretes within fibrous membrane and calcified
Intramembraneous ossification step 3
Woven bone and periosteum form
Intramembraneous ossification step four
Lamellar bone replaces woven bone, deep to periosteum. Red marrow appears
Endochondral ossification
Cartilage bone forms by replacing hyaline cartilage
Uses hyaline cartilage as model
Forms most of the rest of the Skelton
Endochondral ossification step one
Bone collar forms around hyaline cartilage model
Endochondral ossification step two
Cartilage in the center of the diaphysis calcified and develops cavities
Endochondral ossification step 3
Periosteum bud invades internal cavities and spongy bone begins to form
Endochondral ossification step 4
Diaphysis elongates
Medullary cavity forms
Secondary ossification centers appear in epiphysis
Endochondral ossification step 5
Epiphysis ossify
At the end of endochondral ossification where is hyaline cartilage
At end hyaline cartilage remains only in epiphyseal plates and articulate cartilage