Orthomyxoveridae Flashcards
How many genera are found in the Orthomyxoviridae family of viruses? A. 4 B. 7 C. 5 D. 6
C. 5
What are hemagglutinin and neuraminidase?
A. Proteins found in the nucleus of influenza virus
B. Secretory proteins produced by the orthomyxovirus
C. Lipoprotein ligands on orthomyxovirus target cells
D. Glycoproteins on orthomyxovirus that contribute to virus attachment
D. Glycoproteins on orthomyxovirus that contribute to virus attachment
Which of the following sentences best describes the type and configuration of the nucleic acid in orthomyxovirus?
A. 6-8 segments of linear, negative sense, single stranded RNA
B. 6-8 segments of circular, negative sense sense, dsDNA
C. 6-8 segments of circular, positive sense dsRNA
D. 6-8 segments of linear, positive sense, single stranded RNA
A. 6-8 segments of linear, negative sense, single stranded RNA
When influenza viruses re-assort their gene segments, it is said that they undergo an: A. antigenetic drift B. Antigenic rearrangement C. Antigenic drift D. Antigenic shift
D. Antigenic shift
Retrovirus, orthomyxovirus, and paramyxovirus have lipid envelope and so are sensitive to: A. Acidic pH B. Lipid solvents C. Heat (e.g., 56C/30 min) D. All of the above
D. All of the above
Uncoating of the orthomyxovirus envelope takes place in the: A. None of the above B. Both in nucleus and cytoplasm C. Cytoplasm D. Nucleus
C. Cytoplasm
Which of the following names of an influenze virus is correct according to the naming scheme of influenza viruses? A. A/swine/Iowa/15/30 B. Swine/A/Iowa/15/’30 (H1N1) C. A/Iowa/swine/15/30 (H1N1) D. A/swine/Iowa/15/1930 (H1N1)
D. A/swine/Iowa/15/1930 (H1N1)
Which of the following statements best describes transmission of Influenza virus?
A. In aquatic birds fecal-oral transmission is common
B. In poultry- ingestion and inhalation
C. In mammals- aerosol, droplets, and fomites
D. A, B, and C
D. A, B, and C
What type of horses are at risk of contracting equine influenza? A. Breeding stock horses B. Race horses C. Show horses D. All of the above
D. All of the above
Equine influenza is primarily a disease of the: A. Immune system B. Reproductive tract C. Respiratory tract D. Digestive tract
C. Respiratory tract
Prolonged high fever in pregnant mares infected with equine influenza virus can lead to: A. Emaciation B. Abortion C. No consequence D. Severe dehydration
B. Abortion
What feasible therapeutic options are available for treatment of swine influenza in swine? A. Antivirals B. None exist C. Steroid therapy D. Antibiotics
B. None exist
Which of the following virus families has a herringbone shaped nucleocapsid? A. Picornaviridae B. Orthopoxviridae C. Orthomyxoviridae D. Paramyxoviridae
D. Paramyxoviridae
Which orthomyxovirus genus contains pathogens for humans, swine, horses, and chicken? A. Thogotovirus B. Influenza B C. Influenza A D. Influenza C
C. Influenza A
What diagnostic course would take to assess herd immunity to equine influenza?
A. ELISA, to measure residual virus antigens
B. Biological assay, to challenge animals and see if they will be infected with equine influenza virus
C. RT-PCR, to measure the residual viral RNA
D. Retrospective serology to measure the level of antibodies against equine influenza virus
D. Retrospective serology to measure the level of antibodies against equine influenza virus