Flaviviridae Flashcards

1
Q
In the replication cycle of flaviviruses, once proteins (both non-structional and structional) are translated where do they go?
A. nucleus
B. cell membrane surface
C. golgi apparatus
D. endoplasmic reticulum
A

D. endoplasmic reticulum

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2
Q

flaviviruses are susceptible to lipid solvents as disinfectants.
true or false

A

True

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3
Q
which of the following neurological signs can be observed in WNV-infected horses?
abnormality in gait
muscle fasciculation
head tremors
all of the above
A

All of the above

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4
Q
you think you have recognized WNV infection in a horse on the 5th day of infection, however you still have doubts. What sample and which rapid diagnostic test would you prescribe to confirm?
A. blood, immunohistochemistry
B. blood, virus neutralization
C. blood, rt-pcr
D. blood, Igm ELISA
A

D. blood, IgM ELISA

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5
Q

Ticks can transmit WNV.

true or false

A

True

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6
Q
infection of BVDV in cattle can result in:
A. mucosal disease only
B. none of the above	
C. bovine diarrhea or mucosal disease
D. bovine diarrhea only
A

C. bovine diarrhea or mucosal disease

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7
Q
bovine viral diarrhea virus belongs to the genus?
A. flavivirus
B. pestivirus
C. flaviviridae
D. hepacivoorus
A

B. pestivirus

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8
Q

how is BVDV transmitted?
A. by birds feeding from the same animal feed
B. by mice feeding from the same animal feed
C. by ticks and mosquitoes
D. indirectly by feed and fomites contaminated with urine of infected animals

A

D. indirectly by feed and fomites contaminated with urine of infected animals

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9
Q

what is the consequence of infection of cattle with a non-cytopathic BVDV strain?

A. Acute mucosal disease
B. persistent infection with sporadic mucosal disease
C. acute viral diarrhea
D. subacute viral diarrhea

A

B. persistent infection with sporadic mucosal disease

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10
Q

At what stage of gestation can infection with BVDV in cows terminate the pregnancy, cause embryonic death or if the pregnancy is carried to term, persistently infected calves can e born?

A. Second trimester
B. third trimester
C. fourth trimester
D. first trimester

A

D. first trimester

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11
Q

if a cow is infected with a non-cytopathic strain of BVDV it will develop a persistent infection. What is the outcome of co-infection of such an animal with a cytopathic BVDV strain?

A. No clinical disease because it partly immune
B. mucosal disease
C. subacute diarrhea
D. acute viral diarrhea disease

A

B. mucosal disease

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12
Q

persistent or prenatal infection with BVDV in cattle can lead to genetic disorders of fetuses.

true or false

A

true

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13
Q

you are an international veterinary consultant. What advice would you give to a developing country on the control of BVDV?

A. Vaccinate all animals
B. identify infected animals, eliminate and vaccinate new animals in the herd
C. separate infected animals from healthy animals
D. no steps necessary, the disease will appear on its own

A

B. identify infected animals, eliminate and vaccinate new animals in the herd

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14
Q
classical swine fever is also referred to as:
A. hog fever
B. typhus
C. african swine fever
D. hog cholera
A

D. hog cholera

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15
Q
Hog cholera is typically a disease of:
A. horses
B. dogs
C. cattle
D. pigs
A

D. pigs

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16
Q

where in north america is classical swine fever enzootic?
A. Canada
B. mexico
C. currently, classical swine
D. fever is not found in north america USA

A

D. fever is not found in north america USA

17
Q

high fever and abdominal hyperemia are characteristic of classical swine fever
true or false

A

true

18
Q

indicate which of the following is a unique feature of the flavivirus replication cycle?
A. virion assembly and encapsidation take place on the cell surface
B. virion assembly and encapsidation take place in the endoplasmic reticulum
C. replicate in the cytoplasm
D. replicate in the nucleus

A

B. virion assembly and encapsidation take place in the endoplasmic reticulum

19
Q

which statement accurately descries the transmission of the west nile virus?
A. Birds are reservoirs, mosquitoes are vectors, horses are amplification hosts
B. Birds are reservoirs, mosquitoes are vectors, horses and humans are amplification hosts
C. Birds are reservoirs, mosquitoes are vectors, humans are amplification hosts
D. Birds are reservoirs, mosquitoes are vectors, horses and humans are accidental hosts

A

D. Birds are reservoirs, mosquitoes are vectors, horses and humans are accidental hosts

20
Q

at what stage of gestation with BVDV of pregnant cows result in early embryonic death or resorption?
A. Early pregnancy
B. late in pregnancy
C. pregnancy before immunological competence
D. none of the above

A

A. Early pregnancy