organisation of the nervous system

Question 1

regeneration capacity difference: CNS vs PNS

Answer 1

axons in PNS can regenerate after injury; axons in CNS have limited regenerative capacity

Question 2

axons in PNS

Answer 2

injury leads to stimulation of phagocytes which remove debris (otherwise inhibit regrowth); may be compromised by aberrant axon sprouting and non-specific target reinnervation, leading to neuropathic pain

Question 3

axons in CNS

Answer 3

glia exert inhibitory influence on regeneration; glial scars form in place of injured brain tissue; absence of guidance cues that stimulate axon growth