cells of the nervous system Flashcards
synapses: explain the distinguishing features of axo-dendritic, axo-somatic and axo-axonic synapses
bouton
common synapse at axon terminal
varicosities
swellings along neurone containing vesicles with neurotransmitter
synaptic structure: density
increased proteins; abundant mitochondria
why do synapses have increased proteins
release of vesicle and action of neurotransmitter (ion channels, pumps, receptors)
why do synapses have abundant mitochondria
ion pumping and synaptic transmission; sensitive to oxygen deprivation
where are synaptic vesicles packaged
Golgi
what transport mechanism ships synaptic vesicles
fast anterograde transport
synaptic vesicle association with plasma membrane
specialised mechanisms
synaptic organisation
neurones receive multiple synaptic inputs; use diversity of chemical transmitters to be excitatory or inhibitory
what is neuronal integration
competing inputs are integrated in postsynaptic neuone
types of synapse
axo-dendritic, axo-somatic, axo-axonic
axo-dendritic synapse function
commonest; excitatory
axo-somatic synapse function
often inhibitory
axo-axonic synapse function
modulatory